Beneficial effect of a low-fat low-calorie diet on myocardial energy metabolism in patients with angina pectoris. | |
MedLine Citation:
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PMID: 6146007 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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8 patients with exertional angina pectoris were treated for 3 months with a low-fat, low-calorie diet. Serum cholesterol was reduced by 28% and body-weight by 7.9 kg on average. The effect of the dietary intervention was assessed by a heart metabolic study during pacing-induced tachycardia. After dietary treatment coronary sinus blood-flow and myocardial oxygen consumption were considerably reduced, but pacing time before angina developed increased. Other improvements were a reduction in lactate release during pacing, a reduction in citrate release during recovery, a reduction in alanine output during rest and recovery, and a lower uptake of glutamate. The results suggest a beneficial effect of low-fat, low-calorie dietary treatment on myocardial energy metabolism in patients with exertional angina pectoris. |
Authors:
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L Thuesen; T T Nielsen; A Thomassen; J P Bagger; P Henningsen |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Lancet Volume: 2 ISSN: 0140-6736 ISO Abbreviation: Lancet Publication Date: 1984 Jul |
Date Detail:
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Created Date: 1984-08-20 Completed Date: 1984-08-20 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 2985213R Medline TA: Lancet Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 59-62 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
MeSH Terms | |
Descriptor/Qualifier:
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Alanine
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metabolism Angina Pectoris / diet therapy*, metabolism, physiopathology Cardiac Pacing, Artificial Citrates / metabolism Citric Acid Dietary Fats / administration & dosage* Energy Intake* Energy Metabolism Glutamates / metabolism Heart Rate Humans Lactates / metabolism Male Middle Aged Myocardium / metabolism* Oxygen Consumption |
Chemical | |
Reg. No./Substance:
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0/Citrates; 0/Dietary Fats; 0/Glutamates; 0/Lactates; 56-41-7/Alanine; 77-92-9/Citric Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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