| Beneficial effect of coronary artery bypass grafting as assessed by quantitative gated single-photon emission computed tomography. | |
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MedLine Citation:
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PMID: 12808266 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The development of quantitative gated single-photon emission computed tomography (SPECT) has enabled the assessment of left ventricular perfusion, function and wall thickness in a single examination. Accordingly, the present study used gated SPECT to assess the benefit of coronary artery bypass grafting (CABG) in patients with coronary artery disease; 47 of those patients were evaluated before and 5 months after CABG. As a result of coronary revascularization, a significant improvement was observed in global ejection fraction (50+/-12 --> 53+/-11%; p<0.05). In 107 revascularized territories, the average regional reversible defect score (0.8+/-0.5 --> 0.2 +/-0.3; p<0.0001), average regional perfusion score at rest (0.6+/-0.6 --> 0.3+/-0.4; p<0.0001), average regional wall motion score (0.9+/-0.7 --> 0.7+/-0.5; p<0.05), and end-diastolic wall thickness (8.1+/-1.3 --> 8.6+/-1.5 mm; p<0.0005) all improved significantly. Even in 34 non-revascularized territories, the average regional reversible defect score (0.5+/-0.7 --> 0.2+/-0.5; p<0.03), average regional wall motion score (0.8+/-1.1 --> 0.5 +/-1.0; p<0.03) and end-diastolic wall thickness (8.0+/-1.4 --> 9.1+/-2.0 mm; p<0.03) all improved significantly. These results indicate that improvement in myocardial ischemia, hibernation and left ventricular function with CABG can be assessed in detail with gated SPECT. |
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Authors:
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Satoshi Hida; Taishiro Chikamori; Tetsuzo Hirayama; Yasuhiro Usui; Hidefumi Yanagisawa; Takayuki Morishima; Shin Ishimaru; Akira Yamashina |
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Publication Detail:
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Type: Evaluation Studies; Journal Article |
Journal Detail:
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Title: Circulation journal : official journal of the Japanese Circulation Society Volume: 67 ISSN: 1346-9843 ISO Abbreviation: Circ. J. Publication Date: 2003 Jun |
Date Detail:
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Created Date: 2003-06-16 Completed Date: 2004-01-23 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 101137683 Medline TA: Circ J Country: Japan |
Other Details:
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Languages: eng Pagination: 499-504 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine II, Tokyo Medical University, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Coronary Artery Bypass* Diastole Female Follow-Up Studies Heart / radionuclide imaging* Humans Male Middle Aged Myocardial Ischemia / physiopathology Myocardial Stunning / physiopathology Myocardium / pathology Stroke Volume Surgical Procedures, Elective Systole Tomography, Emission-Computed, Single-Photon* / methods Treatment Outcome Ventricular Function, Left |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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