| Effect of silicon gel sheeting in nasal injury associated with nasal CPAP in preterm infants. | |
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MedLine Citation:
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PMID: 19430064 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We conducted this study to investigate the efficacy of the silicon gel application on the nares in prevention of nasal injury in preterm infants ventilated with nasal continuous positive airway pressure (NCPAP). Patients (n=179) were randomized into two groups: Group 1 (n=87) had no silicon gel applied to nares, and in Group 2 (n=92), the silicon gel sheeting was used on the surface of nares during ventilation with NCPAP. Nasal injury developed in 13 (14.9%) neonates in Group 1 and 4 (4.3%) newborns in Group 2 (OR:3.43; 95% CI: 1.1-10.1; P<0.05). The incidence of columella necrosis was also significantly higher in the Group 1 (OR: 6.34; 95% CI: 0.78-51.6; P<0.05). We conclude that the silicon gel application may reduce the incidence and the severity of nasal injury in preterm infants on nasal CPAP. |
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Authors:
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Ayla Günlemez; Tonguç Isken; Ayse S Gökalp; Gülcan Türker; Engin A Arisoy |
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Publication Detail:
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Type: Journal Article; Randomized Controlled Trial Date: 2009-04-15 |
Journal Detail:
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Title: Indian pediatrics Volume: 47 ISSN: 0974-7559 ISO Abbreviation: Indian Pediatr Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-04-07 Completed Date: 2010-07-12 Revised Date: 2010-11-15 |
Medline Journal Info:
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Nlm Unique ID: 2985062R Medline TA: Indian Pediatr Country: India |
Other Details:
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Languages: eng Pagination: 265-7 Citation Subset: IM |
Affiliation:
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Section of Neonatology, Department of Pediatrics; and Department of Plastic, Reconstructive and Aesthetic Surgery; Kocaeli University Faculty of Medicine, Kocaeli, Turkey. aylagunlemez@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Topical Continuous Positive Airway Pressure / adverse effects, methods* Gels Humans Infant, Newborn Infant, Premature Necrosis Nose / injuries* Prospective Studies Silicon / administration & dosage* Wounds and Injuries / etiology, prevention & control |
| Chemical | |
Reg. No./Substance:
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0/Gels; 7440-21-3/Silicon |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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