| Behind heart failure syndrome: remember AL amyloidosis. Two case-reports. | |
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MedLine Citation:
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PMID: 21309362 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Amyloidosis is a systemic disease that is a consequence of extracellular deposition of insoluble fibrils composed of subunits of low molecular weight (5-25 kD) derived from a variety of plasma proteins. Identification of the amyloidogenic protein determines the type of amyloidosis. In primary systemic amyloidosis (classically called AL amyloidosis), the amyloid protein is composed of light chains resulting from plasma-cell dyscrasia. Cardiac manifestations are the most common clinical presentation of this type of amyloidosis, occurring in 50% of patients. The authors describe two cases in which hospitalization was due to decompensated heart failure, which were similar in their etiology (multiple myeloma/amyloid cardiomyopathy) and evolution (sudden death). The authors wish to draw attention to an entity that is rarely encountered in clinical practice and that requires a high index of suspicion. |
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Authors:
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Doroteia Silva; Luís Sargento; Manuel Gato Varela; Dulce Brito; Mário G Lopes |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Revista portuguesa de cardiologia : orgão oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology Volume: 29 ISSN: 0870-2551 ISO Abbreviation: Rev Port Cardiol Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2011-02-11 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8710716 Medline TA: Rev Port Cardiol Country: Portugal |
Other Details:
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Languages: eng; por Pagination: 1751-9 Citation Subset: IM |
Affiliation:
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Serviço de Cardiologia I, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, EPE, Lisboa, Portugal. dojreis@hotmail.com |
Export Citation:
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Descriptor/Qualifier:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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