| Behcet's disease: experience in a tertiary rheumatology centre in Singapore and a review of the literature. | |
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MedLine Citation:
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PMID: 15329766 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: The only reported study on Behcet's disease (BD) in Singapore found that only 15% of 34 BD patients managed at a tertiary dermatology centre had arthritis and 6% had eye complications with no other systemic manifestations. The aim of our study was to characterise the clinical manifestations and outcome of patients with BD at a tertiary rheumatology centre in Singapore. MATERIALS AND METHODS: The International Study Group (ISG) and the O'Duffy (OD) criteria were used. The demographics, manifestations and outcome of our patients with BD were recorded. RESULTS: Thirty-seven patients were included in our study. Twenty-three (62.2%) satisfied both ISG and OD criteria. Fourteen (37.8%) did not fulfil the ISG criteria but fulfilled the OD criteria and of these 6 were the incomplete form and 8 the complete form. The male to female ratio was 1:1.1. The mean age of onset of disease was 32.7 years (range, 15 to 58 years). The commonest presentations were recurrent oral ulcers (37, 100%), genital ulcers (24, 64.9%), joint (21, 56.8%) and cutaneous manifestations (18, 48.6%). The most common systemic manifestations were arthritis (16, 43.2%), gastrointestinal manifestations (15, 40.5%) and uveitis (13, 35.1%). There were 2 cases of Neuro Behcet's and 2 cases of venous thrombosis. Visual impairment from uveitis was the commonest cause of morbidity. There were no deaths in our series of BD. CONCLUSION: BD is a relatively rare rheumatologic condition in Singapore. However, because its systemic complications are not rare, early diagnosis and prompt treatment are essential. |
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Authors:
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Y K Cheng; B Y Thong; H H Chng |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Annals of the Academy of Medicine, Singapore Volume: 33 ISSN: 0304-4602 ISO Abbreviation: Ann. Acad. Med. Singap. Publication Date: 2004 Jul |
Date Detail:
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Created Date: 2004-08-26 Completed Date: 2004-11-19 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7503289 Medline TA: Ann Acad Med Singapore Country: Singapore |
Other Details:
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Languages: eng Pagination: 510-4 Citation Subset: IM |
Affiliation:
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Department of Rheumatology, Allergy & Immunology, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433. yew_kuang_cheng@ttsh.com.sg |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Behcet Syndrome / diagnosis*, physiopathology Female Humans Male Middle Aged Singapore |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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