| Behavioural and physiological effects of electrical stimulation in the nucleus accumbens: a review. | |
| | |
MedLine Citation:
|
PMID: 17691326 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Electrical stimulation (ES) in the brain is becoming a new treatment option in patients with treatment-resistant obsessive-compulsive disorder (OCD). A possible brain target might be the nucleus accumbens (NACC). This review aims to summarise the behavioural and physiological effects of ES in the NACC in humans and in animals and to discuss these findings with regard to neuroanatomical, electrophysiological and behavioural insights. The results clearly demonstrate that ES in the NACC has an effect on reward, activity, fight-or-flight, exploratory behaviour and food intake, with evidence for only moderate physiological effects. Seizures were rarely observed. Finally, the results of ES studies in patients with treatment-resistant OCD and in animal models for OCD are promising. |
| | |
Authors:
|
K van Kuyck; L Gabriëls; P Cosyns; L Arckens; V Sturm; S Rasmussen; B Nuttin |
Related Documents
:
|
21056796 - Congenital abnormalities in production animals. 15200096 - Quality control of the private veterinary profession in the netherlands. 1688046 - Sarcocystis in caribou (rangifer tarandus terraenorae) in newfoundland. 7941266 - Movement of food animals within the single market. 16227176 - Migration modelling from food-contact plastics into foodstuffs as a new tool for consum... 3830236 - Short term lead exposure, age and food deprivation: interactive effects on wheel runnin... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
|
Title: Acta neurochirurgica. Supplement Volume: 97 ISSN: 0065-1419 ISO Abbreviation: Acta Neurochir. Suppl. Publication Date: 2007 |
Date Detail:
|
Created Date: 2007-08-13 Completed Date: 2007-09-26 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 100962752 Medline TA: Acta Neurochir Suppl Country: Austria |
Other Details:
|
Languages: eng Pagination: 375-91 Citation Subset: IM |
Affiliation:
|
Laboratory of Experimental Neurosurgery and Neuroanatomy, Department of Neuroscience and Psychiatry, Leuven Provisorium, Belgium. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Behavior, Animal / physiology, radiation effects* Disease Models, Animal Eating / physiology, radiation effects Electric Stimulation / methods* Exploratory Behavior / physiology, radiation effects Humans Nucleus Accumbens / physiology*, radiation effects* Obsessive-Compulsive Disorder / therapy Reward |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Neurosurgery for psychiatric disorders: from the excision of brain tissue to the chronic electrical ...
Next Document: Neuromodulation of the inferior thalamic peduncle for major depression and obsessive compulsive diso...