| Behaviour of meiotic univalents during metaphase I: natural variants and computer simulations. | |
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MedLine Citation:
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PMID: 4075845 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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When univalent chromosomes are present at first meiotic division, their behaviour is highly variable. In some cases, both sister kinetochores orient towards the same pole (syntely) while in others, the two kinetochores orient to opposite poles (amphitely). The former may be accompanied by recurrent pole-to-pole oscillation, although, as the present report suggests, this is not the only variation which can be found in conjunction with syntelic orientation. This study attempts to explain this diversity of orientation phenomena. A computer model was constructed which can generate all of the common univalent behaviours. Simulation experiments suggest that chromosome length is critical in determining whether amphitelic or syntelic orientation will predominate. Syntely should be common among large univalents, but oscillations will be rare or absent if the chromosome has any capacity for microtubule attachment at its non-centromeric end. It appears that gross attributes of the chromosome may influence the orientation of univalents during the first meiotic division, with consequent effects on the probability of transmission to the next generation. |
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Authors:
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G B Peters |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Cytobios Volume: 43 ISSN: 0011-4529 ISO Abbreviation: Cytobios Publication Date: 1985 |
Date Detail:
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Created Date: 1986-02-10 Completed Date: 1986-02-10 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0207227 Medline TA: Cytobios Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 179-98 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Centromere / physiology Chromosomes / physiology Genetic Variation* Grasshoppers Male Meiosis* Metaphase* Microcomputers Microtubules / physiology Models, Genetic* Spermatocytes / cytology |
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