| Behavioral thermoregulation by hypoxic rats. | |
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MedLine Citation:
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PMID: 1583464 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To address whether a shift in hypothalamic thermal setpoint might be a significant factor in induction of hypoxic hypothermia, behavioral thermoregulation was examined in 7 female Sprague-Dawley rats implanted with radiotelethermometers for deep body temperature (Tb) measurement in a thermocline during normoxia (PO2 = 125 torr) and hypoxia (PO2 = 60 torr). Normoxic rats (TNox) selected a mean ambient temperature of 19.7 +/- 1.4 (SE) degrees C and maintained Tb at 37.0 +/- 0.2 degrees C. Hypoxic rats selected a significantly higher ambient temperature (THox = 28.6 +/- 2.2 degrees C) but maintained Tb significantly lower at 35.5 +/- 0.3 degrees C. Without a thermal gradient (ambient temperature = 25 degrees C), Tb during hypoxia was 35.4 +/- 0.4 degrees C. The maintenance of a lower body temperature during hypoxia through behavioral thermoregulation despite having warmer temperatures available supports the hypothesis that the thermoregulatory setpoint of hypoxic rats is shifted to promote thermoregulation at a lower Tb, effectively reducing oxygen demand when oxygen supply is limited. |
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Authors:
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R K Dupré; T L Owen |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of experimental zoology Volume: 262 ISSN: 0022-104X ISO Abbreviation: J. Exp. Zool. Publication Date: 1992 May |
Date Detail:
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Created Date: 1992-06-12 Completed Date: 1992-06-12 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0375365 Medline TA: J Exp Zool Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 230-5 Citation Subset: IM |
Affiliation:
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Department of Biological Sciences, University of Nevada, Las Vegas 89154. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Behavior, Animal / physiology* Body Temperature Regulation / physiology* Female Oxygen / metabolism* Rats Rats, Inbred Strains |
| Chemical | |
Reg. No./Substance:
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7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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