Document Detail


Behavioral and biological indicators of impulsivity in the development of alcohol use, problems, and disorders.
MedLine Citation:
PMID:  20491733     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Alcohol use disorders (AUDs) are a devastating public health problem. The construct of impulsivity is biologically based and heritable, and its various dimensions are relevant for understanding alcohol use. The goal of the current manuscript is to review recent behavioral and biological research examining various dimensions of impulsivity and their relation to AUDs from risk for initial use through dependence and relapse. Moreover, we also highlight key psychological variables including affective processes as they relate to current use and early indications of alcohol problems, as well as psychopathology, violence, and aggression in relation to AUDs. Each section includes a critical summary and we conclude the review with future directions focused on issues relevant to measurement, causality, and intervention. Throughout the review, we attempt to be as specific as possible about the dimensions of impulsivity being referenced, while attempting to draw parallels and highlighting differences as the existing literature allows.
Authors:
C W Lejuez; Jessica F Magidson; Suzanne H Mitchell; Rajita Sinha; Michael C Stevens; Harriet de Wit
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review     Date:  2010-05-14
Journal Detail:
Title:  Alcoholism, clinical and experimental research     Volume:  34     ISSN:  1530-0277     ISO Abbreviation:  Alcohol. Clin. Exp. Res.     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-26     Completed Date:  2011-04-19     Revised Date:  2012-04-27    
Medline Journal Info:
Nlm Unique ID:  7707242     Medline TA:  Alcohol Clin Exp Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  1334-45     Citation Subset:  IM    
Affiliation:
Department of Psychology, University of Maryland, Center for Addictions, Personality and Emotion Research, Maryland 20742, USA. clejuez@psyc.umd.edu
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MeSH Terms
Descriptor/Qualifier:
Alcohol Drinking / genetics,  pathology,  psychology
Alcohol-Related Disorders / genetics,  pathology,  psychology*
Alcoholism / etiology,  genetics,  psychology
Animals
Humans
Impulsive Behavior / complications,  genetics,  psychology*
Risk Factors
Grant Support
ID/Acronym/Agency:
P60 AA010760/AA/NIAAA NIH HHS; R01 DA018647-08/DA/NIDA NIH HHS; R01 DA019405-01A2/DA/NIDA NIH HHS; R01 DA019405-02/DA/NIDA NIH HHS; R01 DA019405-03/DA/NIDA NIH HHS; R01 DA019405-03S1/DA/NIDA NIH HHS; R01 DA019405-04/DA/NIDA NIH HHS; R01 DA09133/DA/NIDA NIH HHS; R01 DA18647/DA/NIDA NIH HHS; UL1-DE019586/DE/NIDCR NIH HHS
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