Document Detail


Behavior of visfatin in nonobese women undergoing liposuction: a pilot study.
MedLine Citation:
PMID:  20884903     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
INTRODUCTION: The adipocyte has recently begun to be considered not just as a fat deposition tissue, but also as a true endocrine organ. Adipose tissue produces a wide variety of adipocytokines, of which visfatin is one.
OBJECTIVE: Since visfatin has recently been described as a mimic of insulin action, the authors evaluate visfatin behavior in women undergoing liposuction.
MATERIALS: Nineteen nonobese women underwent liposuction of abdominal fat. Patient visfatin levels and a lipid profile were obtained preoperatively, and the results were compared with the results of the same tests immediately postoperatively and one month postoperatively.
RESULTS: The mean age of the 19 study participants was 33 years; mean body mass index was 24.7±2.2 kg/m2. The amount of subcutaneous fat obtained was an average of 4468±1403 kg. Visfatin increased from 51.8±24.4 ng/mL preoperatively to 76.3±39.8 ng/mL (P=.02). Pre- and postoperative lipid profiles reflected, respectively, the following: total cholesterol, 159.1±37.1 vs 164.6±31.7 mg/dL (P=.420); high-density cholesterol, 41.4±8.6 vs 39.3±9.9 mg/dL (P=.421); low-density cholesterol, 97.1±25.4 vs 100±19.2 mg/dL (P=.507); and triglycerides, 92.3±57.1 vs 126.3±72.5 mg/dL (P=.058).
CONCLUSIONS: Visfatin levels were shown to increase after liposuction of subcutaneous fat. The authors conclude that this adipocyte may play an important role as a regulatory reciprocal mechanism.
Authors:
José Antonio Robles-Cervantes; Tanger Castillo-Salcedo; José Guerrerosantos; Manuel González-Ortiz; Esperanza Martínez-Abundis; Juan Francisco Llamas-Moreno; Maria Guadalupe Ramos-Zavala; Martha Patricia Gallegos-Arreola
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Aesthetic surgery journal / the American Society for Aesthetic Plastic surgery     Volume:  30     ISSN:  1527-330X     ISO Abbreviation:  Aesthet Surg J     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-10-01     Completed Date:  2011-01-13     Revised Date:  2011-09-12    
Medline Journal Info:
Nlm Unique ID:  9707469     Medline TA:  Aesthet Surg J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  730-2     Citation Subset:  IM    
Affiliation:
Reconstructive Surgery Institute, Health Ministry, Guadalajara, Mexico. durun@megared.net.mx
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MeSH Terms
Descriptor/Qualifier:
Adipocytes / metabolism
Adult
Cholesterol / blood
Female
Humans
Intra-Abdominal Fat
Lipectomy*
Middle Aged
Nicotinamide Phosphoribosyltransferase / blood*,  metabolism
Pilot Projects
Subcutaneous Fat, Abdominal / metabolism*,  surgery
Triglycerides / blood
Young Adult
Chemical
Reg. No./Substance:
0/Triglycerides; 57-88-5/Cholesterol; EC 2.4.2.12/Nicotinamide Phosphoribosyltransferase
Comments/Corrections
Comment In:
Aesthet Surg J. 2010 Sep;30(5):733-4   [PMID:  20884904 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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