Document Detail

Behavior of artificially produced holes in lung parenchyma.
MedLine Citation:
PMID:  908679     Owner:  NLM     Status:  MEDLINE    
Spherical and cylindrical holes were cut in the parenchyma of isolated dog lung lobes. The holes were insufflated with tantalum dust and the hole diameters were measured along the deflation limb of the lobe pressure-volume curve from transpulmonary pressures of 20 to 0 cmH2O. Hole volume as a fraction of lobe volume was found to be independent of transpulmonary pressure. The hole volume relative to the amount of tissue removed was used to determine the displacement at the hole boundary. A comparison of this displacement with the displacement predicted by a continuum mechanics analysis provides evidence for the applicability of the methods of continuum mechanics and further evidence that the shear modulus of the parenchyma is relatively small.
S J Lai-Fook; R E Hyatt; J R Rodarte; T A Wilson
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Publication Detail:
Type:  In Vitro; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of applied physiology: respiratory, environmental and exercise physiology     Volume:  43     ISSN:  0161-7567     ISO Abbreviation:  J Appl Physiol Respir Environ Exerc Physiol     Publication Date:  1977 Oct 
Date Detail:
Created Date:  1977-11-30     Completed Date:  1977-11-30     Revised Date:  2013-09-26    
Medline Journal Info:
Nlm Unique ID:  7801242     Medline TA:  J Appl Physiol Respir Environ Exerc Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  648-55     Citation Subset:  IM    
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MeSH Terms
Lung / physiopathology
Lung Injury*
Stress, Mechanical

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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