| Bedside testing for myasthenia gravis: the ice-test. | |
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MedLine Citation:
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PMID: 21788239 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Summary A 67-year-old man presented to the acute medical take with a history of droopy eyelids and difficulty swallowing. A diagnosis of myasthenia gravis was suspected from the clinical history. The patient's symptoms were progressive, raising concerns of aspiration pneumonia or respiratory compromise if untreated. Definitive diagnosis of myasthenia gravis relies upon a combination of serological and electrophysiological investigations, the results of which are not immediately available in an acute situation. Bedside tests are therefore of practical clinical importance to enable prompt and effective initiation of treatment, particularly where critical symptoms are present. The ice-test is a straightforward and non-invasive investigation with a high sensitivity for myasthenia gravis and is a useful alternative to edrophonium testing. It is especially helpful in patients with cardiac and respiratory co-morbidities for whom acetylcholinesterase inhibitors are contraindicated. We describe a case where this simple bedside test successfully expedited the correct treatment and improved patient care. |
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Authors:
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J Browning; M Wallace; J Chana; J Booth |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Emergency medicine journal : EMJ Volume: 28 ISSN: 1472-0213 ISO Abbreviation: Emerg Med J Publication Date: 2011 Aug |
Date Detail:
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Created Date: 2011-07-26 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100963089 Medline TA: Emerg Med J Country: England |
Other Details:
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Languages: eng Pagination: 709-11 Citation Subset: IM |
Affiliation:
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mwallace@doctors.org.uk. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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