Document Detail

Bedside intracoronary thrombolysis in the coronary care unit.
MedLine Citation:
PMID:  3581835     Owner:  NLM     Status:  MEDLINE    
Using a mobile X-ray unit in the coronary care unit (CCU), intracoronary streptokinase (IC STK) administration was performed in 20 patients with acute myocardial infarction who arrived 2 to 5 hours after onset of symptoms. IC STK was infused at a rate of 4000 U/min. Of 20 patients, 17 had complete and 3 subtotal occlusion of the infarct-related artery. The IC STK infusion resulted within 15 to 80 min in reperfusion in 12 of 17 patients with occluded artery (70%). One patient died, 4 patients underwent early bypass grafting, in one PTCA was attempted and in one a femoral A-V fistula caused by the procedure required surgical revision. IC STK infusion is much more economical if performed in the CCU and the 24-hour coverage can be provided by an experienced invasive cardiologist on call service.
U Babić; P Pejcić; Z Djuricić; S Grujicić; S Janković; M Vucinić
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cor et vasa     Volume:  29     ISSN:  0010-8650     ISO Abbreviation:  Cor Vasa     Publication Date:  1987  
Date Detail:
Created Date:  1987-06-26     Completed Date:  1987-06-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372614     Medline TA:  Cor Vasa     Country:  CZECHOSLOVAKIA    
Other Details:
Languages:  eng     Pagination:  1-8     Citation Subset:  IM    
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MeSH Terms
Coronary Care Units*
Coronary Disease / drug therapy*
Coronary Thrombosis / drug therapy*
Infusions, Intra-Arterial
Middle Aged
Myocardial Infarction / drug therapy
Streptokinase / administration & dosage,  adverse effects,  therapeutic use*
Reg. No./Substance:
EC 3.4.-/Streptokinase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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