Document Detail


Bedside cardiology and thrombolysis.
MedLine Citation:
PMID:  8227786     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The study by Christian et al. (37) provides useful clinical information for the management of the patient with myocardial infarction with thrombolytic therapy. 1) Complete resolution of chest pain during the infusion of an intravenous thrombolytic agent suggests reperfusion and myocardial salvage. Initial conservative medical management should be considered in these patients especially if serial ECGs show a progressive and rapid downward defection of the ST segment. 2) Patients presenting within 6 h after the onset of infarction, who are pain free, may still benefit from thrombolysis if their ECGs show persistent ischemia. 3) In the remaining patients in whom chest pain does not resolve completely during thrombolytic therapy, management, whether continued medical or invasive strategy, should be individualized and dictated by the extent of myocardium at risk (i.e., by the number of ECG leads showing ST segment elevation), the response of the ST segment to thrombolysis and, most important, the clinical status of the patient.
Authors:
H G Olson
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Publication Detail:
Type:  Comment; Editorial    
Journal Detail:
Title:  Journal of the American College of Cardiology     Volume:  22     ISSN:  0735-1097     ISO Abbreviation:  J. Am. Coll. Cardiol.     Publication Date:  1993 Nov 
Date Detail:
Created Date:  1993-12-03     Completed Date:  1993-12-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8301365     Medline TA:  J Am Coll Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1317-9     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Angina Pectoris / etiology*
Humans
Myocardial Infarction / drug therapy*,  mortality*,  radionuclide imaging
Thrombolytic Therapy*
Treatment Outcome
Comments/Corrections
Comment On:
J Am Coll Cardiol. 1993 Nov 1;22(5):1311-6   [PMID:  8227785 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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