| Beat-to-beat change in "myocardial performance index" related to load. | |
| | |
MedLine Citation:
|
PMID: 17430314 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: This study was designed to assess the relationship of the "myocardial performance index" (MPI) to the beat-by-beat change in pre-load with static or unchanged contractile status. METHODS: Eight anesthetized juvenile pigs were studied using direct measurement of the left ventricular pressure and volume. Transient inflation of a vena cava balloon catheter produced controlled pre-load alterations. Consecutive beats were analyzed, grouped for first, second, third, etc. during the pre-load alteration, and evaluated for the change in MPI during the same contractile status with a controlled pre-load alteration. Two pharmacologic inotropic interventions were also included to generate several myocardial conditions in each animal. RESULTS: MPI demonstrated a strong linear relationship to the pre-load and after-load. MPI increased progressively during decreasing end-diastolic volume, mostly related to changes in ejection time. MPI was observed at the same level for three different myocardial function conditions (all eight animals), with a different relationship between MPI and pre-load noted for each observation. CONCLUSIONS: MPI is strongly load dependent, and can vary widely in value for the same contractile status if the load is varied. The use of this index in critically ill patients should be limited in this respect. Further work is needed to establish the relationship of MPI to load and contractile status. |
| | |
Authors:
|
M F Haney; R A'Roch; G Johansson; J Poelaert; B Biber |
Related Documents
:
|
8184774 - The relationship between altered load and impaired diastolic function in conscious dogs... 8266804 - The influence of afterload on uniformity of segment shortening in feline left ventricle... 2773794 - Correlation between histomorphometric findings on endomyocardial biopsy and clinical fi... 6490674 - Incremental elastic modulus for ventricles in diastole. 1928084 - Effects of erythropoietin on blood pressure. 51584 - Correlation of blood pressure with skinfold thickness and protein levels. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Acta anaesthesiologica Scandinavica Volume: 51 ISSN: 0001-5172 ISO Abbreviation: Acta Anaesthesiol Scand Publication Date: 2007 May |
Date Detail:
|
Created Date: 2007-04-13 Completed Date: 2007-07-17 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0370270 Medline TA: Acta Anaesthesiol Scand Country: England |
Other Details:
|
Languages: eng Pagination: 545-52 Citation Subset: IM |
Affiliation:
|
Anesthesia and Intensive Care Medicine, University Hospital of Umeå, S-901 85 Umeå, Sweden. michael.haney@anestesi.umu.se |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Blood Pressure / physiology Epinephrine / pharmacology Isoflurane / pharmacology Myocardial Contraction / drug effects*, physiology Myocardial Revascularization / methods Stroke Volume Swine Vasoconstrictor Agents / pharmacology |
| Chemical | |
Reg. No./Substance:
|
0/Vasoconstrictor Agents; 26675-46-7/Isoflurane; 51-43-4/Epinephrine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Stroke volume variation during hemorrhage and after fluid loading: impact of different tidal volumes...
Next Document: The effect of combining intermittent hemodiafiltration with forced alkaline diuresis on plasma myogl...