Document Detail


Bazedoxifene (Wyeth).
MedLine Citation:
PMID:  15535430     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Bazedoxifene is a tissue-specific selective estrogen receptor modulator being developed by Wyeth Pharmaceuticals (formerly Wyeth-Ayerst Laboratories) to be used alone for the prevention and treatment of osteoporosis in postmenopausal women and in combination with Premarin for menopausal symptoms. As of March and June 2004, worldwide phase III trials for bazedoxifene, and bazedoxifene in combination with Premarin, were ongoing.
Authors:
Christian Gruber; Doris Gruber
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in investigational drugs (London, England : 2000)     Volume:  5     ISSN:  1472-4472     ISO Abbreviation:  Curr Opin Investig Drugs     Publication Date:  2004 Oct 
Date Detail:
Created Date:  2004-11-10     Completed Date:  2005-01-25     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  100965718     Medline TA:  Curr Opin Investig Drugs     Country:  England    
Other Details:
Languages:  eng     Pagination:  1086-93     Citation Subset:  IM    
Affiliation:
Department of Gynecological Endocrinology and Reproductive Medicine, University of Vienna Medical School, A-1090 Vienna, Wahringer Gurtel 18-20, Austria. christian_gruber@chello.at
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MeSH Terms
Descriptor/Qualifier:
Animals
Clinical Trials as Topic
Female
Humans
Indoles / adverse effects,  pharmacokinetics,  therapeutic use*
Osteoporosis, Postmenopausal / drug therapy*,  metabolism,  prevention & control
Receptors, Estrogen / metabolism
Selective Estrogen Receptor Modulators / adverse effects,  pharmacokinetics,  therapeutic use*
Structure-Activity Relationship
Treatment Outcome
Chemical
Reg. No./Substance:
0/Indoles; 0/Receptors, Estrogen; 0/Selective Estrogen Receptor Modulators; 0/bazedoxifene acetate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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