Document Detail

Basilar artery thrombosis in a child heterozygous for factor V Leiden mutation.
MedLine Citation:
PMID:  11182285     Owner:  NLM     Status:  MEDLINE    
Activated protein C resistance, usually because of factor V Leiden mutation, is considered to be the most common hereditary prothrombotic condition. A 9-year-old male with a basilar artery stroke and activated protein C resistance is described. The patient, found to be heterozygous for factor V Leiden mutation, is one of several recent reports that suggest that activated protein C resistance is an important risk factor for spontaneous arterial thrombosis in infancy and childhood.
A Verdú; M R Cazorla; M A Granados; J A Alonso; L F Casado
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric neurology     Volume:  24     ISSN:  0887-8994     ISO Abbreviation:  Pediatr. Neurol.     Publication Date:  2001 Jan 
Date Detail:
Created Date:  2001-02-22     Completed Date:  2001-05-21     Revised Date:  2006-05-23    
Medline Journal Info:
Nlm Unique ID:  8508183     Medline TA:  Pediatr Neurol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  69-71     Citation Subset:  IM    
Pediatric Neurology Unit, Hospital Virgen de la Salud, Toledo, Spain.
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MeSH Terms
Activated Protein C Resistance / diagnosis,  genetics*
Basilar Artery* / pathology
Cerebral Angiography
Factor V / genetics*
Heterozygote Detection
Intracranial Embolism / diagnosis,  genetics*
Magnetic Resonance Imaging
Reg. No./Substance:
0/factor V Leiden; 9001-24-5/Factor V

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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