Document Detail


Basic study on small intestinal motility with various nutrients in supposed post-esophagectomy nutritional support.
MedLine Citation:
PMID:  20187525     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purposes of this study were to record the small intestinal motility induced by different compositions (carbohydrate, protein, fat) of enteral nutrients and to define the effects of each composition on the motility of the small intestine in supposed postesophagectomy nutritional support. Strain-gauge force transducers were used to measure intestinal motility in rats. The change ratio of the maximum amplitude of small intestinal contractions in the fat solution (140.6 +/- 46.5%) and the protein solution (123.9 +/- 34.0%) was significantly less than in the carbohydrate solution (222.0 +/- 107.8%) in the proximal small intestine (P < 0.05). The transportation ability in the fat solution (47.9 +/- 6.4%) and in the protein solution (36.5 +/- 4.9%) was less than in the carbohydrate solution (54.1 +/- 9.2%). Especially in the protein solution, the transportation ability was significantly less than in the carbohydrate solution (P < 0.05). The carbohydrate solution increased small intestinal motility the most. In terms of postoperative nutritional support for patients undergoing an esophagectomy, the above findings indicate that an enteral diet composed of more protein and fat might be appropriate for patients with accelerated small intestinal motility; on the contrary, a carbohydrate-rich diet should be used for patients with decreased small intestinal motility.
Authors:
Satoshi Nara; Narihide Goseki; Tatsuyuki Kawano
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International surgery     Volume:  94     ISSN:  0020-8868     ISO Abbreviation:  Int Surg     Publication Date:    2009 Jul-Sep
Date Detail:
Created Date:  2010-03-01     Completed Date:  2010-03-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0043524     Medline TA:  Int Surg     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  273-8     Citation Subset:  IM    
Affiliation:
Department of Surgery, Tokyo Medical and Dental University Hospital, Tokyo, Japan. tnara@east.ntt.co.jp
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MeSH Terms
Descriptor/Qualifier:
Animals
Dietary Carbohydrates / administration & dosage
Dietary Fats / administration & dosage
Dietary Proteins / administration & dosage
Enteral Nutrition*
Esophagectomy*
Gastrointestinal Motility / drug effects,  physiology*
Intestine, Small / physiology*
Male
Rats
Rats, Sprague-Dawley
Transducers
Chemical
Reg. No./Substance:
0/Dietary Carbohydrates; 0/Dietary Fats; 0/Dietary Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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