Document Detail

Basic mechanisms of reentrant arrhythmias.
MedLine Citation:
PMID:  11124712     Owner:  NLM     Status:  MEDLINE    
The mechanisms responsible for active cardiac arrhythmias are generally divided into two major categories: (1) enhanced or abnormal impulse formation and (2) reentry. Reentry can be subdivided into three subcategories: (1) circus movement, (2) reflection, and (3) Phase 2 reentry. Reentry occurs when a propagating impulse fails to die out after normal activation of the heart and persists to re-excite the heart after expiration of the refractory period. Evidence implicating reentry as a mechanism of cardiac arrhythmias stems back to the turn of the century. Amplification of intrinsic electrical heterogeneities provides the substrate responsible for developing Phase 2 and circus movement reentry, which underlie ventricular tachycardia in the long QT and Brugada syndromes.
C Antzelevitch
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in cardiology     Volume:  16     ISSN:  0268-4705     ISO Abbreviation:  Curr. Opin. Cardiol.     Publication Date:  2001 Jan 
Date Detail:
Created Date:  2001-01-26     Completed Date:  2001-02-22     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8608087     Medline TA:  Curr Opin Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1-7     Citation Subset:  IM    
Masonic Medical Research Laboratory, Utica, New York, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Arrhythmias, Cardiac / physiopathology*
Heart Conduction System / physiopathology*
Models, Cardiovascular*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The predominant form in which neurofilament subunits undergo axonal transport varies during axonal i...
Next Document:  Arrhythmogenic right ventricular dysplasia: cardiomyopathy current opinions on diagnostic and therap...