Document Detail

Basic and clinical aspects of gastrointestinal pain.
MedLine Citation:
PMID:  19155134     Owner:  NLM     Status:  MEDLINE    
The gastrointestinal (GI) tract is a system of organs within multicellular animals which facilitates the ingestion, digestion, and absorption of food with subsequent defecation of waste. A complex arrangement of nerves and ancillary cells contributes to the sensorimotor apparatus required to subserve such essential functions that are with the exception of the extreme upper and lower ends of the GI tract normally subconscious. However, it also has the potential to provide conscious awareness of injury. Although this function can be protective, when dysregulated, particularly on a chronic basis, the same system can lead to considerable morbidity. The anatomical and molecular basis of gastrointestinal nociception, conditions associated with chronic unexplained visceral pain, and developments in treatment are presented in this review.
Charles H Knowles; Qasim Aziz
Related Documents :
21651474 - The fetal origins of obesity: early origins of altered food intake.
21907624 - Energy density, nutrient adequacy, and cost per serving can provide insight into food c...
15081044 - Post-genomics of lactic acid bacteria and other food-grade bacteria to discover gut fun...
22434264 - Suppressive effects of n-acetyl-d: -glucosamine on rheumatoid arthritis mouse models.
172454 - Histopathological effect of clostridium perfringens enterotoxin in the rabbit ileum.
16245834 - A novel method for determination of size resolved, submicrometer particle traffic emiss...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2009-01-19
Journal Detail:
Title:  Pain     Volume:  141     ISSN:  1872-6623     ISO Abbreviation:  Pain     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2009-02-02     Completed Date:  2009-04-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7508686     Medline TA:  Pain     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  191-209     Citation Subset:  IM    
Neurogastroenterology Group, Centres for Academic Surgery, Barts and the London NHS Trust and the Homerton, University NHS Foundation Trust, 3rd Floor Alexandra Wing, Royal London Hospital, London E1 1BB, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Gastrointestinal Tract / pathology*,  physiopathology*
Pain / pathology*,  physiopathology*
Visceral Afferents / physiopathology
Grant Support
//Medical Research Council

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Post-treatment of banknote printing wastewater using polysilicate ferro-aluminum sulfate (PSFA).
Next Document:  Anthelmintic resistance in Swedish sheep flocks based on a comparison of the results from the faecal...