Document Detail


Baseline STD prevalence in a community intervention trial of the female condom in Kenya.
MedLine Citation:
PMID:  11221128     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: We present baseline sexually transmitted disease (STD) prevalence rates from an ongoing intervention trial at Kenyan agricultural sites. METHODS: After gaining the cooperation of management, we identified six matched pairs of tea, coffee, and flower plantations and enrolled approximately 160 women at each site. Six intervention sites received an information programme and distributed female and male condoms, while six control sites received male condoms only and similar information about them. At clinic visits, we tested participants for cervical gonorrhoea (GC) and Chlamydia trachomatis (CT) by ligase chain reaction on urine specimens, and Trichomonas vaginalis (TV) by culture. The study has 80% power to detect a 10% prevalence difference during follow up, assuming a combined STD prevalence of 20%, 25% loss to follow up and intracluster correlation coefficient (ICC) of 0.03. RESULTS: Participants at intervention and control sites (total 1929) were similar at baseline. Mean age was 33 years, the majority were married, more than half currently used family planning, 78% had never used male condoms, and 9% reported more than one sexual partner in the 3 months before the study. Prevalences of GC, CT, and TV were 2.6%, 3.2%, and 20.4% respectively (23.9% overall), and were similar at intervention and control sites. The ICC for STD prevalence was 0.0011. Baseline STD was associated with unmarried status, non-use of family planning, alcohol use, and more than one recent sexual partner, but the highest odds ratio was 1.5. CONCLUSIONS: Baseline results confirm a high prevalence of trichomoniasis and bacterial STD at these Kenyan rural sites. Improved STD management is urgently needed there. Our ongoing female condom intervention trial is feasible as designed.
Authors:
P J Feldblum; M Kuyoh; M Omari; K A Ryan; J J Bwayo; M Welsh
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Publication Detail:
Type:  Clinical Trial; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Sexually transmitted infections     Volume:  76     ISSN:  1368-4973     ISO Abbreviation:  Sex Transm Infect     Publication Date:  2000 Dec 
Date Detail:
Created Date:  2001-02-26     Completed Date:  2001-03-08     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  9805554     Medline TA:  Sex Transm Infect     Country:  England    
Other Details:
Languages:  eng     Pagination:  454-6     Citation Subset:  IM    
Affiliation:
Family Health International (FHI), PO Box 13950, Research Triangle Park, NC 27709, USA. pfeldblum@fhi.org
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Alcohol Drinking
Chlamydia Infections / epidemiology*,  prevention & control
Chlamydia trachomatis*
Condoms, Female / supply & distribution*
Female
Gonorrhea / epidemiology*,  prevention & control
Humans
Kenya / epidemiology
Marital Status
Mass Screening / methods
Middle Aged
Odds Ratio
Prevalence
Regression Analysis
Risk Factors
Rural Health / statistics & numerical data
Sexual Partners
Trichomonas Vaginitis / epidemiology*,  prevention & control
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