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Baseline Characteristics and Management of Patients with Atrial Fibrillation/flutter in the Emergency Department: Results of a Prospective, Multicenter Registry in China.
MedLine Citation:
PMID:  24893684     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: There have been several studies of atrial fibrillation (AF) over the past decades; however, data from Chinese patients are scarce. The aim of the study was therefore to describe the patient characteristics, risk profile and management strategies for Chinese AF patients presenting to emergency department (ED).
METHODS: We conducted a prospective, multicenter registry of patients with AF or atrial flutter (AFL) in China. Participants were enrolled at 20 EDs, then data regarding baseline characteristics and treatment in EDs were collected.
RESULTS: Of the 2016 Chinese patients, 1104 (54.8%) were female. 618 (30.7%) had paroxysmal AF, 452 (22.4%) had persistent AF and 945 (46.9%) had permanent AF. The most common comorbidity was hypertension (55.5%), followed by coronary artery disease (41.8%), and heart failure (37.4%). The prevalence of concomitant cardiovascular risk factors, such as heart failure and valvular heart disease, increased as AF progressed. Among the patients with non-valvular atrial fibrillation (NVAF), 110 (12.7%) of those with CHADS2 ≥2 were prescribed oral anticoagulants (OACs), while 119 (15.6%) of those with CHADS2 <2 received such agents. Among the 324 patients with valvular atrial fibrillation (VAF), 134 (41.4%) actually were treated with OACs. The INR value was within the target range (2.0-3.0) in 96 patients only (26.4%). Moreover, a total of 16.2% of the patients received ≥1 antiarrhythmic agents (AADs), whereas rate-control agents were used more frequently (68.4%).
CONCLUSIONS: According to the present study, the risk profile and management of Chinese patients with AF/AFL differed from that observed in previous studies. The use of OACs inadequately deviate from current guidelines.
Authors:
Han Zhang; Yanmin Yang; Jun Zhu; Xinghui Shao; Yao Liu; Li Zhao; Pengfei Yu; Hua Zhang; Qing He; Xiaodan Gu
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-6-3
Journal Detail:
Title:  Internal medicine journal     Volume:  -     ISSN:  1445-5994     ISO Abbreviation:  Intern Med J     Publication Date:  2014 Jun 
Date Detail:
Created Date:  2014-6-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101092952     Medline TA:  Intern Med J     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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This article is protected by copyright. All rights reserved.
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