Document Detail

Baseline Characteristics and Management of Patients with Atrial Fibrillation/flutter in the Emergency Department: Results of a Prospective, Multicenter Registry in China.
MedLine Citation:
PMID:  24893684     Owner:  NLM     Status:  Publisher    
BACKGROUND: There have been several studies of atrial fibrillation (AF) over the past decades; however, data from Chinese patients are scarce. The aim of the study was therefore to describe the patient characteristics, risk profile and management strategies for Chinese AF patients presenting to emergency department (ED).
METHODS: We conducted a prospective, multicenter registry of patients with AF or atrial flutter (AFL) in China. Participants were enrolled at 20 EDs, then data regarding baseline characteristics and treatment in EDs were collected.
RESULTS: Of the 2016 Chinese patients, 1104 (54.8%) were female. 618 (30.7%) had paroxysmal AF, 452 (22.4%) had persistent AF and 945 (46.9%) had permanent AF. The most common comorbidity was hypertension (55.5%), followed by coronary artery disease (41.8%), and heart failure (37.4%). The prevalence of concomitant cardiovascular risk factors, such as heart failure and valvular heart disease, increased as AF progressed. Among the patients with non-valvular atrial fibrillation (NVAF), 110 (12.7%) of those with CHADS2 ≥2 were prescribed oral anticoagulants (OACs), while 119 (15.6%) of those with CHADS2 <2 received such agents. Among the 324 patients with valvular atrial fibrillation (VAF), 134 (41.4%) actually were treated with OACs. The INR value was within the target range (2.0-3.0) in 96 patients only (26.4%). Moreover, a total of 16.2% of the patients received ≥1 antiarrhythmic agents (AADs), whereas rate-control agents were used more frequently (68.4%).
CONCLUSIONS: According to the present study, the risk profile and management of Chinese patients with AF/AFL differed from that observed in previous studies. The use of OACs inadequately deviate from current guidelines.
Han Zhang; Yanmin Yang; Jun Zhu; Xinghui Shao; Yao Liu; Li Zhao; Pengfei Yu; Hua Zhang; Qing He; Xiaodan Gu
Related Documents :
23761394 - Human atrial fibrillation substrate: towards a specific fibrotic atrial cardiomyopathy.
9952094 - The pencan 25-gauge needle: a new pencil-point needle for spinal anesthesia tested in 1...
7105504 - Middle molecular weight substances in the cerebrospinal fluid of uremic patients.
16236614 - Fludarabine may induce durable remission in patients with leptomeningeal involvement of...
20356864 - Markers of proteolysis, fibrinolysis, and coagulation in relation to size and growth ra...
3259934 - Calcitonin-related peptides in patients with acute leukemia: association of human calci...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-6-3
Journal Detail:
Title:  Internal medicine journal     Volume:  -     ISSN:  1445-5994     ISO Abbreviation:  Intern Med J     Publication Date:  2014 Jun 
Date Detail:
Created Date:  2014-6-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101092952     Medline TA:  Intern Med J     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
This article is protected by copyright. All rights reserved.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Asp68His mutation in the A1 domain of human factor V causes impaired secretion and ineffective trans...
Next Document:  Hepatocellular carcinoma in cirrhotic patients with transjugular intrahepatic portosystemic shunt: A...