| Base deficit level indicating major injury is increased with ethanol. | |
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MedLine Citation:
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PMID: 10699516 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Analyses were performed to determine whether ethanol increases base deficit, independent of major injury, in blunt trauma patients from two Level I trauma centers. In 2140 Baltimore patients, base deficit was significantly higher in ethanol-positive patients (blood level > or =0.01%), independent of blood pressure (BP), Injury Severity Score (ISS), and blood loss. In 139 Youngstown, Ohio, patients, base deficit was significantly higher in ethanol-positive patients, independent of ISS and RBC units given. In 1796 awake Baltimore patients, major injury was defined as an ISS >10, presence of blood loss, or need for RBC transfusion. A base deficit < or =-4.1 for ethanol-positive and < or =-1.1 for ethanol-negative patients had higher rates of major injury (odds ratio 3.2 and 2.1, respectively) and abdominal trauma (odds ratio 3.6 and 3.2, respectively). In blunt trauma patients, base deficit is increased with ethanol, independent of major injury. A base deficit of < or =-4.1 for ethanol-positive and < or =-1.1 for ethanol-negative awake patients may be an early warning for occult injury and suggest the need for an abdominal computed tomography (CT) scan or ultrasound. |
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Authors:
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C M Dunham; L A Watson; C Cooper |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: The Journal of emergency medicine Volume: 18 ISSN: 0736-4679 ISO Abbreviation: J Emerg Med Publication Date: 2000 Feb |
Date Detail:
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Created Date: 2000-03-30 Completed Date: 2000-03-30 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8412174 Medline TA: J Emerg Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 165-71 Citation Subset: IM |
Affiliation:
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St. Elizabeth Trauma Center, Youngstown, Ohio 44501-1790, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abdominal Injuries
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blood,
epidemiology Acid-Base Imbalance / blood*, epidemiology* Alcohol Drinking / blood*, epidemiology* Cohort Studies Comorbidity Ethanol / blood Evaluation Studies as Topic Female Humans Incidence Injury Severity Score Lactic Acid / blood* Male Maryland / epidemiology Multivariate Analysis Ohio / epidemiology Predictive Value of Tests Regression Analysis Risk Factors Sampling Studies Trauma Centers Wounds, Nonpenetrating / blood*, diagnosis, epidemiology* |
| Chemical | |
Reg. No./Substance:
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50-21-5/Lactic Acid; 64-17-5/Ethanol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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