| Basal insulin analogues--a review of recent data on efficacy and safety. | |
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MedLine Citation:
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PMID: 21818995 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Conventional basal insulin preparations have to be resuspended prior to injection and have low therapeutic efficacy and drawbacks like nocturnal hypoglycaemia. There is evidence supporting improved pharmacokinetic and pharmacodynamic profiles of basal insulin analogues, glargine and detemir as compared with NPH. Initiation and titration of basal insulin analogues helps patients to improve compliance due to low injection frequency compared to the conventional basal insulin. The unique protraction mechanism adds advantage to insulin detemir in terms of high predictability. Also these analogues have better patient adherence, improved quality of life and higher treatment satisfaction. So basal insulin analogues particularly are better treatment options for treatment of diabetes. |
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Authors:
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Mathew John |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of the Association of Physicians of India Volume: 59 Suppl ISSN: 0004-5772 ISO Abbreviation: J Assoc Physicians India Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-08-08 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7505585 Medline TA: J Assoc Physicians India Country: India |
Other Details:
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Languages: eng Pagination: 25-8 Citation Subset: IM |
Affiliation:
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Providence Endocrine & Diabetes Specialty Centre, Thiruvananthapuram 695013, India. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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