Document Detail

Basal and exercise-induced changes in plasma catecholamines: relationship to age, smoking habits and sampling times.
MedLine Citation:
PMID:  7554764     Owner:  NLM     Status:  MEDLINE    
Contrary to earlier investigations, we have previously shown that the initial increase in venous plasma noradrenaline (NA) during exercise did not differ in young and elderly non-smoking subjects exercising at the same relative workload (75%), and that the greatest increase at maximal workload was observed in the young subjects. In order to determine whether the observed discrepancy could be explained by long-term smoking, plasma NA and adrenaline (A) were evaluated in eight elderly male smokers (mean age 67 years). The results were compared with data reported previously [Jensen et al. (1994) Exercise-induced changes in plasma catecholames and neuropeptide Y: relation to age and sampling times. J Appl Physiol, 76, 1269-1273] in seven young (mean age 27 years) and seven elderly (mean age 61 years) non-smoking male subjects. As shown earlier, basal plasma NA was significantly increased in elderly smokers compared to young and elderly non-smokers. During exercise at 75% of maximal work capacity, no difference was observed between elderly smokers and non-smokers. No difference in plasma A was found between elderly smokers and non-smokers either at rest or during exercise. These findings indicate that the exercise-induced increase in plasma NA did not differ in elderly smokers and non-smokers despite increased resting levels in the former group, and that the increase in the elderly subjects was not augmented compared to that in young subjects.
E W Jensen; K Espersen; I L Kanstrup; N J Christensen
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical physiology (Oxford, England)     Volume:  15     ISSN:  0144-5979     ISO Abbreviation:  Clin Physiol     Publication Date:  1995 Jul 
Date Detail:
Created Date:  1995-11-21     Completed Date:  1995-11-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8309768     Medline TA:  Clin Physiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  299-305     Citation Subset:  IM    
Department of Internal Medicine and Endocrinology, Herlev University Hospital, Denmark.
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MeSH Terms
Aging / blood*
Catecholamines / blood*
Epinephrine / blood
Exercise / physiology*
Exercise Test
Heart Rate / physiology
Middle Aged
Norepinephrine / blood
Oxygen Consumption
Smoking / blood*
Time Factors
Reg. No./Substance:
0/Catecholamines; 51-41-2/Norepinephrine; 51-43-4/Epinephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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