| Bartter's syndrome in pregnancy: review of potassium homeostasis in gestation. | |
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MedLine Citation:
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PMID: 19770791 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 26-year-old G3P2 Hispanic female presented with acute urinary retention and profound hypokalemia (serum potassium 1.6 mEq/L) during her 13th week of pregnancy. Placement of an indwelling bladder catheter resulted in immediate urine output of 1700 mL. Potassium was administered aggressively and urinary retention resolved. She reported the use of herbal products containing licorice and corn silk tea (zea maize extract). She was taking no medication other than prenatal vitamins and had no known prior medical problems. Despite discontinuance of the herbal supplement and tea and aggressive oral potassium replacement, severe asymptomatic hypokalemia persisted. Twenty-four-hour urine studies and blood chemistry determinations, subsequently, were consistent with Bartter's syndrome. At the time of hospital discharge, she was receiving 480 mEq of oral potassium daily. Potassium-sparing diuretics were not prescribed, because successful pregnancy outcomes have been reported in patients with Bartter's syndrome and Gitelman syndrome without normalization of potassium levels. Hypokalemia (2.5-3.0 mEq/L) persisted throughout an otherwise uncomplicated pregnancy with delivery of a healthy child at 35 weeks of gestation. |
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Authors:
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Ashar Luqman; Asif Kazmi; Barry M Wall |
Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: The American journal of the medical sciences Volume: 338 ISSN: 1538-2990 ISO Abbreviation: Am. J. Med. Sci. Publication Date: 2009 Dec |
Date Detail:
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Created Date: 2009-12-17 Completed Date: 2010-01-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370506 Medline TA: Am J Med Sci Country: United States |
Other Details:
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Languages: eng Pagination: 500-4 Citation Subset: AIM; IM |
Affiliation:
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University of Tennessee Health Science Center, Memphis, Tennessee, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Bartter Syndrome / complications*, drug therapy, metabolism*, physiopathology Female Homeostasis Humans Hypokalemia / complications, drug therapy, metabolism Infant, Newborn Potassium / administration & dosage, metabolism* Pregnancy Pregnancy Complications / drug therapy, metabolism*, physiopathology Renal Circulation Renin-Angiotensin System / physiology |
| Chemical | |
Reg. No./Substance:
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7440-09-7/Potassium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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