Document Detail

Barrier pressure at the gastroesophageal junction in anesthetized dogs.
MedLine Citation:
PMID:  11453482     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate the effect of body position on barrier pressure at the gastroesophageal junction in anesthetized Greyhounds and to assess alterations in barrier pressure following gastropexy. ANIMALS: 8 adult Greyhounds. PROCEDURE: Barrier pressure at the gastroesophageal junction was measured by fast (1 cm/s) and slow (1 cm/10 s) withdrawal of a subminiature strain gauge transducer through the gastroesophageal junction in 8 anesthetized dogs. The effect of body position was measured. Each dog then was placed in right-lateral recumbency, and gastropexy was performed in the left flank. Additional measurements were obtained 1, 5, 10, 20, and 30 minutes after gastropexy. RESULTS: Barrier pressure for dogs positioned in sternal recumbency (mean +/- SEM, 1.1 +/- 0.53 mm Hg) was significantly less than for dogs positioned in right lateral or left lateral recumbency. Following gastropexy, there was a steady increase in barrier pressure. Thirty minutes after gastropexy, barrier pressure was significantly higher (13.36 +/- 3.46 mm Hg), compared with the value before surgery. CONCLUSIONS AND CLINICAL RELEVANCE: Barrier pressure in anesthetized dogs is highly variable and influenced by body position. This is most likely the result of anatomic interrelationships between the diaphragm, stomach, and terminal portion of the esophagus. Gastropexy also increases barrier pressure in the immediate postoperative period, which may be clinically relevant in terms of understanding how resolution of gastroesophageal reflux disease associated with hiatal hernia may be affected by gastropexy combined with hernia reduction.
K M Pratschke; C R Bellenger; H McAllister; D Campion
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  American journal of veterinary research     Volume:  62     ISSN:  0002-9645     ISO Abbreviation:  Am. J. Vet. Res.     Publication Date:  2001 Jul 
Date Detail:
Created Date:  2001-07-16     Completed Date:  2001-12-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0375011     Medline TA:  Am J Vet Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1068-72     Citation Subset:  IM    
Department of Veterinary Surgery, Faculty of Veterinary Medicine, University College Dublin, Ballsbridge, Ireland.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Abdominal Muscles / surgery
Anesthesia, General / adverse effects,  veterinary*
Anesthetics, Inhalation / administration & dosage
Anesthetics, Intravenous / administration & dosage
Digestive System Surgical Procedures / veterinary
Dogs / physiology*,  surgery
Esophagogastric Junction / physiology*
Halothane / administration & dosage
Laparotomy / veterinary
Methohexital / administration & dosage
Posture / physiology
Transducers, Pressure / veterinary
Reg. No./Substance:
0/Anesthetics, Inhalation; 0/Anesthetics, Intravenous; 151-67-7/Halothane; 18652-93-2/Methohexital

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Uptake of beta-carotene by ovarian and uterine tissues and effects on steroidogenesis during the est...
Next Document:  Comparison of medetomidine and dexmedetomidine as premedicants in dogs undergoing propofol-isofluran...