Document Detail


Baroreceptor denervation presenting as part of a vagal mononeuropathy.
MedLine Citation:
PMID:  10823338     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 48-year-old woman presented with a history of progressive cough, dysphonia, dysphagia, and postural symptoms. Subsequent neurological investigations were consistent with a bilateral vagal mononeuropathy, and neurosarcoidosis was diagnosed after scalene node biopsy. Autonomic investigations including microneurography, neurohormones, and heart rate variability demonstrated arterial and cardiopulmonary baroreflex failure. In addition, parasympathetic control of heart rate was absent and consistent with a bilateral, nonselective lesion in the proximal vagus.
Authors:
D L Jardine; I C Melton; S I Bennett; I G Crozier; I M Donaldson; H Ikram
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical autonomic research : official journal of the Clinical Autonomic Research Society     Volume:  10     ISSN:  0959-9851     ISO Abbreviation:  Clin. Auton. Res.     Publication Date:  2000 Apr 
Date Detail:
Created Date:  2000-07-19     Completed Date:  2000-07-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9106549     Medline TA:  Clin Auton Res     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  69-75     Citation Subset:  IM    
Affiliation:
Cardiology Department, Christchurch Hospital, New Zealand. davidj@chhlth.govt.nz
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MeSH Terms
Descriptor/Qualifier:
Arginine Vasopressin / blood
Autonomic Nervous System Diseases / physiopathology*
Blood Pressure
Electrocardiography
Female
Heart Rate
Humans
Middle Aged
Muscles / innervation
Norepinephrine / blood
Pressoreceptors / physiopathology*
Renin / blood
Sympathetic Nervous System / physiopathology
Tilt-Table Test
Vagus Nerve / physiopathology*
Chemical
Reg. No./Substance:
113-79-1/Arginine Vasopressin; 51-41-2/Norepinephrine; EC 3.4.23.15/Renin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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