Document Detail

Bariatric surgery and renal function: a precarious balance between benefit and harm.
MedLine Citation:
PMID:  20566568     Owner:  NLM     Status:  MEDLINE    
Medical treatment of obesity and lifestyle modification have limited effectiveness in treating it in morbidly obese individuals. Importantly, bariatric surgery is regarded as the only therapy that is effective in maintaining significant weight loss in morbidly obese individuals. Despite the fact that bariatric surgery-induced weight loss is associated with a significant decrease in morbidity and mortality and improvement in renal function, bariatric surgery has recently been shown to be associated with a significant risk of nephrolithiasis. The main risk factor for nephrolithiasis is increased excretion of urinary oxalate. In this review, we discuss the association between bariatric surgery, an increased risk of renal stone formation and oxalate nephropathy.
Mohamed H Ahmed; Christopher D Byrne
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Publication Detail:
Type:  Journal Article; Review     Date:  2010-06-21
Journal Detail:
Title:  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association     Volume:  25     ISSN:  1460-2385     ISO Abbreviation:  Nephrol. Dial. Transplant.     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-23     Completed Date:  2011-01-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8706402     Medline TA:  Nephrol Dial Transplant     Country:  England    
Other Details:
Languages:  eng     Pagination:  3142-7     Citation Subset:  IM    
Chemical Pathology Department, Southampton University Hospitals NHS Trust, Southampton, UK.
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MeSH Terms
Adiponectin / blood
Bariatric Surgery / adverse effects*
Calcium Oxalate / metabolism
Hyperoxaluria / etiology
Interleukin-18 / blood
Kidney / physiopathology*
Kidney Calculi / etiology*
Obesity, Morbid / physiopathology*
Reg. No./Substance:
0/Adiponectin; 0/Interleukin-18; 25454-23-3/Calcium Oxalate
Comment In:
Nephrol Dial Transplant. 2010 Dec;25(12):4116-7; author reply 4117-8   [PMID:  20921300 ]

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