Document Detail


Barcode technology in yeast: application to pharmacogenomics.
MedLine Citation:
PMID:  20846145     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
The common baker's yeast, Saccharomyces cerevisiae, is one of the oldest domesticated organisms known, and has been exploited by our ancestors in several different applications, particularly in food and fermentations industries and in bioconversion and biodegradation processes. Over the years, yeast has become an excellent experimental model for biological and medical studies, thanks to its genetic tractability, well-known physiology and fast-doubling cycle. In the last decade, the advances in genome sequencing opened the doors to high-throughput studies and yeast quickly has become a model system for drug discovery and mode of action. This review provides a focused overview of the achievements in the field of human medicine and pharmacology by exploiting the molecular tools available for yeast.
Authors:
Daniela Delneri
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  FEMS yeast research     Volume:  10     ISSN:  1567-1364     ISO Abbreviation:  FEMS Yeast Res.     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-08     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101085384     Medline TA:  FEMS Yeast Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  1083-9     Citation Subset:  IM    
Copyright Information:
© 2010 Federation of European Microbiological Societies. Published by Blackwell Publishing Ltd. All rights reserved.
Affiliation:
Faculty of Life Sciences, University of Manchester, Manchester, UK. d.delneri@manchester.ac.uk
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