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Band ligation or sclerotherapy as endoscopic treatment for oesophageal varices in schistosomotic patients: results of a randomized study.
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MedLine Citation:
PMID:  9830578     Owner:  NLM     Status:  MEDLINE    
Endoscopic sclerotherapy and banding ligation are the two preferred methods to treat oesophageal variceal bleeding. There are many reports dealing with such treatment in cirrhotic patients but we do not know how good they are to treat varices secondary to other forms of portal hypertension. Schistosomiasis mansoni is the main cause of portal hypertension and oesophageal varices in Brazil. We performed a prospective randomised study to compare: 1) the efficacy of both treatments in eradicating oesophageal varices, and 2) complications secondary to both treatments. Forty patients were divided in two groups. Both sclerotherapy and banding ligation were performed until variceal eradication. There were no severe complications. Variceal eradication was faster obtained with banding ligation than sclerotherapy although there was no statistical difference (mean number of sessions 3.05 vs 3.72, p = 0.053). Benign complications were equally frequent in both groups, although additional sedation was more common in the sclerotherapy group. We concluded that both treatments are equally effective in the eradication of oesophageal varices, although banding ligation is better tolerated by the patient and probably faster.
E S Siqueira; M R Rohr; E D Libera; R R Castro; A P Ferrari
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  HPB surgery : a world journal of hepatic, pancreatic and biliary surgery     Volume:  11     ISSN:  0894-8569     ISO Abbreviation:  HPB Surg     Publication Date:  1998  
Date Detail:
Created Date:  1999-01-28     Completed Date:  1999-01-28     Revised Date:  2008-11-20    
Medline Journal Info:
Nlm Unique ID:  9002972     Medline TA:  HPB Surg     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  27-32     Citation Subset:  IM    
Division of Gastroenterology, Universidade Federal de São Paulo, Escola Paulista de Medicina.
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MeSH Terms
Endoscopy / methods*,  statistics & numerical data
Esophageal and Gastric Varices / etiology,  therapy*
Esophagoplasty / methods*,  statistics & numerical data
Esophagoscopy / methods*,  statistics & numerical data
Gastrointestinal Hemorrhage / etiology,  therapy*
Ligation / methods,  statistics & numerical data
Middle Aged
Oleic Acids / administration & dosage
Prospective Studies
Schistosomiasis mansoni / complications,  therapy*
Sclerosing Solutions / administration & dosage
Sclerotherapy / methods*,  statistics & numerical data
Statistics, Nonparametric
Reg. No./Substance:
0/Oleic Acids; 0/Sclerosing Solutions; 3282-75-5/ethanolamine oleate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Full Text
Journal Information
Journal ID (nlm-ta): HPB Surg
ISSN: 0894-8569
ISSN: 1607-8462
Publisher: Hindawi Publishing Corporation
Article Information
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Copyright ? 1998 Hindawi Publishing Corporation.
open-access: This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received Day: 26 Month: 12 Year: 1997
Print publication date: Month: 8 Year: 1998
Volume: 11 Issue: 1
First Page: 27 Last Page: 32
ID: 2423920
PubMed Id: 9830578
Publisher Item Identifier: S0894856998683946
DOI: 10.1155/1998/68394

Band Ligation or Sclerotherapy as Endoscopic Treatment for Oesophageal Varices in Schistosomotic Patients: Results of a Randomized Study
Eduardo Sampaio Siqueira1
Maria Rachel Da Silveria Rohr1
Ermelindo Della Libera1
Rubem Robson O. Castro1
Angelo Paulo Ferrari12
1Endoscopy UnitUniversidade Federal de S?o Paulo-Escola Paulista de MedicinaDivision of GastroenterologyBrazil
2Rua Machado Bittencourt379 apt. 91S?o Paulo-SPCEP 04044-001Brazil

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