Document Detail

The Baltimore activity scale for intermittent claudication: a validation study.
MedLine Citation:
PMID:  17038572     Owner:  NLM     Status:  MEDLINE    
The purpose of this study was to develop and cross-validate the Baltimore Activity Scale for Intermittent Claudication (BASIC) questionnaire in patients with peripheral arterial disease limited by intermittent claudication, and to determine whether the BASIC questionnaire score changed following a supervised program of exercise rehabilitation. A total of 702 consecutive patients with peripheral arterial disease and stable intermittent claudication were characterized on physical activity level using the BASIC questionnaire and an accelerometer. The first 351 patients tested were included in the validation group, whereas the final 351 patients were included in the cross-validation group. Subsequently, 61 of these patients participated in a randomized, controlled trial in which 28 patients completed 6 months of exercise rehabilitation and 24 patients completed usual care control. The sum of 5 questions from the BASIC questionnaire (0-10 point scale) was predictive of daily physical activity using the following regression equation: Daily Physical Activity (kcal/day) = 102.2 + (49.6 x BASIC score); R = 0.76, R(2) = 0.58, standard error of estimate = 52.0 kcal/day, P < .0001. This equation was successfully cross-validated on an independent group of patients, as the predicted daily physical activity (339 - 181 kcal/day, mean - SD) was similar (P = .501) to measured daily physical activity (347 - 266 kcal/day, mean - SD). Furthermore, the BASIC score increased 38% following 6 months of exercise rehabilitation (P < .01), whereas no change was observed in the control group (P > .05). A composite of 5 questions obtained from the self-administered BASIC questionnaire accurately estimates daily physical activity in patients with peripheral arterial disease limited by intermittent claudication, and is sensitive to change in physical activity following a program of exercise rehabilitation.
Andrew W Gardner; Polly S Montgomery
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Validation Studies    
Journal Detail:
Title:  Vascular and endovascular surgery     Volume:  40     ISSN:  1538-5744     ISO Abbreviation:  Vasc Endovascular Surg     Publication Date:    2006 Oct-Nov
Date Detail:
Created Date:  2006-10-13     Completed Date:  2007-01-11     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  101136421     Medline TA:  Vasc Endovascular Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  383-91     Citation Subset:  IM    
CMRI Metabolic Research Center, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA
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MeSH Terms
Exercise Test
Exercise Therapy
Intermittent Claudication / diagnosis*,  etiology,  therapy
Peripheral Vascular Diseases / complications,  diagnosis*,  therapy
Randomized Controlled Trials as Topic
Regression Analysis
Sensitivity and Specificity
Severity of Illness Index
Treatment Outcome
Grant Support
K01-00657//PHS HHS; M01-RR-14467/RR/NCRR NIH HHS; P60-AG12583/AG/NIA NIH HHS; R01-AG-16685/AG/NIA NIH HHS

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