Document Detail

Balloon valvuloplasty for congenital heart disease: immediate and long-term results of multi-institutional study.
MedLine Citation:
PMID:  11737725     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND OBJECTIVES: Several studies have been reported in Japan. However, the reports consist of small series at individual institutions. We evaluated the immediate to long-term results of balloon valvuloplasty (BVP) of congenital pulmonary and aortic stenosis at multi-institutions in Japan. METHODS AND RESULTS: Immediate and follow-up data were obtained from eight institutions in Japan. In our series of 172 cases of pulmonary valvuloplasty excluding critical pulmonary stenosis, the mean pressure gradient decreased immediately after BVP from 61+/-27 mmHg to 28+/-20 mmHg and the reduced gradient continued at follow-up in most cases. The BVP for critical pulmonary stenosis could be accomplished in 35 of 39 patients. The mean right ventricular systolic pressure decreased from 102+/-29 mmHg to 62+/-23 mmHg. One of them required the surgical operation for perforation of the right ventricular outflow tract. In BVP for congenital aortic valvular stenosis of 77 cases excluding critical aortic stenosis, the mean pressure gradient decreased immediately after BVP from 68+/-24 mmHg to 34+/-23 mmHg. Thirty-one cases (55%) were free from any interventions in long-term follow-up. The BVP for critical aortic stenosis was performed in 29 neonates. The overall mortality rate was 34% and 24% of the patients required repeat intervention. The remaining 42% was free from any interventions. CONCLUSIONS: Balloon valvuloplasty for congenital pulmonary valvular stenosis is a safe and effective procedure and the initial treatment of choice. In spite of an occasional major complication, BVP for critical pulmonary stenosis is effective in many infants. Balloon aortic valvuloplasty is palliative. However, this procedure has the efficacy in deferring the surgical intervention. Balloon valvuloplasty for neonatal critical aortic stenosis is a useful method to recover from serious conditions.
S Echigo
Related Documents :
11108695 - Transcatheter atrial septal defect occlusion in piglets by balloon detachable devices.
15547655 - Fibromuscular dysplasia of bilateral brachial arteries--a case report and literature re...
3047085 - Pulmonary valvuloplasty as an alternative to surgery in the pediatric patient: implicat...
21905215 - A simplified in vivo approach for evaluating the bioabsorbable behavior of candidate st...
6772385 - Pathophysiology and treatment of coronary arterial spasm.
8458815 - Chronic hypoxic pulmonary hypertension in the guinea pig: effect of three levels of hyp...
Publication Detail:
Type:  Clinical Trial; Journal Article; Multicenter Study    
Journal Detail:
Title:  Pediatrics international : official journal of the Japan Pediatric Society     Volume:  43     ISSN:  1328-8067     ISO Abbreviation:  Pediatr Int     Publication Date:  2001 Oct 
Date Detail:
Created Date:  2001-12-12     Completed Date:  2002-01-14     Revised Date:  2008-05-21    
Medline Journal Info:
Nlm Unique ID:  100886002     Medline TA:  Pediatr Int     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  542-7     Citation Subset:  IM    
Department of Pediatrics, National Cardiovascular Center, Suita, Osaka, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aortic Valve Stenosis / congenital,  therapy*
Balloon Dilatation* / methods,  standards
Child, Preschool
Critical Care
Follow-Up Studies
Infant, Newborn
Pulmonary Valve Stenosis / congenital,  therapy*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Catheter closure of moderate to large sized patent ductus arteriosus using the simultaneous double o...
Next Document:  Balloon dilatation and stent implantation for vascular stenosis.