Document Detail

Balloon valvuloplasty as an initial palliation in the treatment of newborns and young infants with severely symptomatic tetralogy of Fallot.
MedLine Citation:
PMID:  16254424     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Balloon valvuloplasty in infants with symptomatic tetralogy of Fallot (TOF) may increase the pulmonary flow and prompt the growth of pulmonary arteries. METHOD: From 1994 to 2002, percutaneous transluminal balloon valvuloplasty (PTPV) was performed in 22 consecutive newborns and young infants (<3 months of age) with TOF. The indication included severe hypoxemia (systemic oxygen saturation below 75%, 10 cases) and repeated hypoxic spells (12 cases). The age at PTPV was 8-88 days (38 +/- 34, median 27) and the body weight 2-5 kg (3.45 +/- 1.15, median 3). A balloon catheter (4- 7 mm in diameter and 2 cm in length) was used to dilate the pulmonary valve. RESULTS: No major procedure-related complications occurred. The systemic oxygen saturation increased significantly (14 +/- 9%). A subsequent palliative shunt operation was avoided in 12 patients (54.5%), but 10 still needed operation (median 11 days after the PTPV). The presence of recurrent hypoxic spells before PTPV was the most important indicator for PTPV failure (p = 0.02). CONCLUSION: PTPV was safe and effective for symptomatic newborns and young infants with TOF, but a palliative shunt operation was still needed due to short effect, especially in those with recurrent spells before the dilation.
En-Ting Wu; Jou-Kou Wang; Wen-Lee Lee; Chien-Chih Chang; Mei-Hwan Wu
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2005-10-27
Journal Detail:
Title:  Cardiology     Volume:  105     ISSN:  0008-6312     ISO Abbreviation:  Cardiology     Publication Date:  2006  
Date Detail:
Created Date:  2005-11-25     Completed Date:  2006-03-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1266406     Medline TA:  Cardiology     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  52-6     Citation Subset:  IM    
Copyright Information:
Copyright 2006 S. Karger AG, Basel.
Department of Pediatrics, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan, ROC.
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MeSH Terms
Balloon Dilatation*
Follow-Up Studies
Infant Welfare
Infant, Newborn
Postoperative Complications / etiology
Pulmonary Artery / surgery
Pulmonary Valve / surgery
Severity of Illness Index
Tetralogy of Fallot / therapy*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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