Document Detail


Balloon dilatation of the aortic valve in the fetus: a report of two cases.
MedLine Citation:
PMID:  2039669     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Because they had irreversible damage to the left ventricular myocardium none of 12 patients with critical aortic stenosis diagnosed prenatally survived after postnatal treatment. This experience prompted three attempts at intrauterine balloon dilatation of the aortic valve in two fetuses with this condition. On each attempt the balloon catheter was successfully delivered to the left ventricle. In the first fetus the aortic valve was not crossed and the fetus died the next day. In the second fetus the balloon was correctly positioned across the aortic valve and inflated in the valve ring. After delivery, a further balloon angioplasty was performed; this relieved the stenosis but the patient died five weeks later from persisting left ventricular dysfunction related to endocardial fibroelastosis. Balloon angioplasty is feasible in fetal life but the prognosis depends on the ability of the relief of stenosis to limit, prevent, or allow regression of left ventricular damage before delivery.
Authors:
D Maxwell; L Allan; M J Tynan
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  British heart journal     Volume:  65     ISSN:  0007-0769     ISO Abbreviation:  Br Heart J     Publication Date:  1991 May 
Date Detail:
Created Date:  1991-07-08     Completed Date:  1991-07-08     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0370634     Medline TA:  Br Heart J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  256-8     Citation Subset:  AIM; IM    
Affiliation:
Department of Fetal Medicine, Guy's Hospital, London.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aortic Valve / pathology
Aortic Valve Stenosis / pathology,  therapy*,  ultrasonography
Balloon Dilatation / methods*
Endocardial Fibroelastosis / complications
Female
Fetal Diseases / pathology,  therapy*,  ultrasonography
Fetal Heart / pathology,  ultrasonography
Humans
Pregnancy
Ultrasonography, Prenatal / methods
Comments/Corrections

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