Document Detail


Balloon aortic valvuloplasty for severe aortic stenosis as a bridge to high-risk transcatheter aortic valve implantation.
MedLine Citation:
PMID:  20351386     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: To provide data on feasibility, safety and efficacy of balloon aortic valvuloplasty (BAV) as a bridge to transcatheter aortic valve implantation (TAVI). Background. There are no data on BAV use as a bridge to TAVI in patients at high risk of periprocedural complications. METHODS: Between June 2007 to May 2009, 83 consecutive patients with symptomatic severe aortic stenosis (48 female, 35 male) aged from 65 to 88 years (mean age 81 +/- 5 years) were treated with TAVI. Early hemodynamic and clinical outcomes of patients undergoing palliative BAV before TAVI (BAV Group, n = 43) were compared with those of patients who directly underwent TAVI (no-BAV Group, n = 40). RESULTS: Patients in the BAV group had worse baseline clinical characteristics than those in the no-BAV group, with higher rates of congestive heart failure, New York Heart Association (NYHA) functional class III or IV and a higher EuroSCORE. In the BAV group, significant changes were found after valvuloplasty with regard to NYHA functional class, mean pressure gradient and aortic valve area. Peak-to-peak transvalvular pressure gradient and left ventricular systolic pressure also decreased immediately after BAV. Before TAVI, no differences in either clinical status or hemodynamic data were observed between patients who underwent BAV and those who did not. CONCLUSIONS: Bridging to TAVI with BAV is a feasible and reasonably safe approach to offer temporary relief in selected high-risk patients with symptomatic severe aortic stenosis and a high chance of periprocedural complications.
Authors:
Gian Paolo Ussia; Davide Capodanno; Marco Barbanti; Marilena Scarabelli; Sebastiano Imme; Valeria Cammalleri; Massimiliano Mule; Anna Pistritto; Patrizia Aruta; Corrado Tamburino
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of invasive cardiology     Volume:  22     ISSN:  1557-2501     ISO Abbreviation:  J Invasive Cardiol     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-03-30     Completed Date:  2010-08-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8917477     Medline TA:  J Invasive Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  161-6     Citation Subset:  IM    
Affiliation:
Department of Cardiology, Ferrarotto Hospital, University of Catania, Catania, Italy.
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Angioplasty*
Aortic Valve Stenosis / surgery*
Balloon Dilatation*
Blood Pressure
Feasibility Studies
Female
Heart Valve Prosthesis Implantation*
Humans
Male
Palliative Care*
Preoperative Care
Risk Factors
Treatment Outcome
Comments/Corrections
Comment In:
J Invasive Cardiol. 2010 Apr;22(4):167   [PMID:  20387314 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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