Document Detail

Balloon angioplasty in infants with aortic obstruction after the modified stage I Norwood procedure.
MedLine Citation:
PMID:  10925335     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The incidence of coarctation after stage I Norwood procedure varies between 11% and 37%, and it contributes to late death after this operation. We describe the incidence and report the results of percutaneous balloon angioplasty of neoaortic arch obstruction in patients after the modified Norwood procedure for hypoplastic left heart syndrome (HLHS). METHODS: During a period of 5 years, 136 patients (94 male, 42 female) underwent a first stage modified Norwood procedure for HLHS. All 95 survivors (69.8%) underwent cardiac catheterization before the second stage. Neoaortic arch obstruction was diagnosed on documentation of a peak systolic gradient of >10 mm Hg across the arch associated with angiographic evidence of localized narrowing of the aortic lumen. RESULTS: Twenty-one (22.1%) of the 95 survivors were documented to have neoaortic arch obstruction. Seventeen patients underwent percutaneous balloon angioplasty for the relief of the neoaortic arch obstruction. The predilatation peak gradient across the arch was reduced significantly by angioplasty from 28.6 +/- 16.9 mm Hg (range 10 to 73 mm Hg) to 5.3 +/- 5.2 mm Hg (range 0 to 19 mm Hg) (P <.001). A final gradient <10 mm Hg or <70% of the starting gradient was considered a success. CONCLUSION: The absence of serious sequelae after the procedure or need for reintervention, as shown by our study, makes balloon angioplasty an effective technique and the treatment of choice for the relief of recoarctation of the neoaortic arch in patients with staged palliation of HLHS.
M Chessa; A Dindar; J J Vettukattil; O Stumper; J G Wright; E D Silove; J De Giovanni
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American heart journal     Volume:  140     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  2000 Aug 
Date Detail:
Created Date:  2000-09-05     Completed Date:  2000-09-05     Revised Date:  2006-02-27    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  227-31     Citation Subset:  AIM; IM    
Heart Unit, Birmingham Children's Hospital NHS Trust, Birmingham, UK.
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MeSH Terms
Angioplasty, Balloon*
Aortic Coarctation / etiology,  radiography,  therapy*
Blood Flow Velocity / physiology
Blood Pressure / physiology
Hypoplastic Left Heart Syndrome / radiography,  surgery*
Postoperative Complications / etiology,  radiography,  therapy*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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