Document Detail

Balloon angioplasty of arteries of the upper extremities in patients with extracranial giant-cell arteritis.
MedLine Citation:
PMID:  16464985     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To evaluate the outcome of balloon angioplasty in the arteries of the upper extremities in patients with giant-cell arteritis (GCA) and stenosing extracranial involvement.
METHODS: Percutaneous transluminal angioplasty (PTA) for symptomatic upper limb artery stenoses (n = 29) and occlusions (n = 1) resistant to medical treatment was carried out in 10 patients (all women, mean age 65 years) with GCA. Vascular lesions were located in the subclavian (n = 4), axillary (n = 10) and brachial (n = 16) arteries. Interventional treatment was accompanied by immunosuppressive drugs in all patients. Follow-up included clinical and serological examination, magnetic resonance angiography and colour duplex ultrasound.
RESULTS: Initial technical success of angioplasty was achieved in the case of all vascular lesions. In five patients, marked recurrent stenoses (vascular territories; n = 10/30) were found during follow-up (mean 24 months). The cumulative primary patency rate was 65.2%. All recurrent lesions developed in the territories of the initial long-segment stenoses. Repeated PTA (vascular territories, n = 8; patients, n = 5) provided a cumulative secondary patency rate of 82.6% and a cumulative tertiary patency rate of 89.7%.
CONCLUSIONS: Despite a tendency to restenoses, balloon angioplasty of the upper-extremity artery, in combination with immunosuppressive treatment, is an efficient method for the treatment of extracranial GCA.
M Both; P M Aries; S Müller-Hülsbeck; T Jahnke; P J Schäfer; W L Gross; M Heller; M Reuter
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Publication Detail:
Type:  Evaluation Studies; Journal Article     Date:  2006-02-07
Journal Detail:
Title:  Annals of the rheumatic diseases     Volume:  65     ISSN:  0003-4967     ISO Abbreviation:  Ann. Rheum. Dis.     Publication Date:  2006 Sep 
Date Detail:
Created Date:  2006-08-14     Completed Date:  2006-09-26     Revised Date:  2013-06-07    
Medline Journal Info:
Nlm Unique ID:  0372355     Medline TA:  Ann Rheum Dis     Country:  England    
Other Details:
Languages:  eng     Pagination:  1124-30     Citation Subset:  IM    
Department of Diagnostic Radiology, University Hospital Schleswig-Holstein, Campus Kiel, Arnold-Heller-Strasse 9, 24105 Kiel, Germany.
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MeSH Terms
Angioplasty, Balloon / methods*
Arterial Occlusive Diseases / etiology,  radiography,  therapy*
Combined Modality Therapy
Follow-Up Studies
Giant Cell Arteritis / complications,  radiography,  therapy*
Immunosuppressive Agents / therapeutic use
Middle Aged
Treatment Outcome
Upper Extremity / blood supply*
Vascular Patency
Reg. No./Substance:
0/Immunosuppressive Agents

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