Document Detail

Balloon aortic valvuloplasty for aortic stenosis using a novel percutaneous dilation catheter and power injector.
MedLine Citation:
PMID:  20738729     Owner:  NLM     Status:  In-Data-Review    
Calcific aortic stenosis is the most common valvular heart disease in the Western world. Although definitive treatment is valve replacement, many patients are not replacement candidates due to high surgical risk from older age and comorbid illness or lack of desire for a surgical or replacement procedure. Percutaneous balloon aortic valvuloplasty (BAV) is an option for palliative treatment in nonsurgical patients, although this procedure is complicated during the immediate postprocedure period by bleeding requiring transfusion for about 1 in 5 patients and subsequent restenosis. This report describes BAV using a smaller profile balloon designed to withstand higher pressures, rapidly inflated with a power injector. Twenty consecutive high-risk patients with severe aortic stenosis were treated. In all cases, New York Heart Association (NYHA) class improved from IV before BAV to I or II at 30 days follow-up. Six-month posttreatment follow-up data were available for 19 of 20 patients: 15 patients were either NYHA class I or II, 1 patient was class III, and 3 deaths occurred unrelated to aortic stenosis. One patient was lost to follow-up. Average systolic gradient peak-to-peak pressure decreased by 40.0% (range 18.0-70.0%) and mean gradient decreased by 30.0% (range 13.7-70.8%). Aortic valve area increased from 0.59 ± 0.16 cm(2) to 0.92 ± 0.23 cm(2) , representing a mean increase of 30.0% (range 7.8%-58.2%). There were no significant bleeding complications. The only procedural complication was a single case of pericardial tamponade. There were no other complications during the first 24 hours post-BAV. These data support that the reported BAV technique may offer an effective alternative for patients with severe aortic stenosis who are not surgical candidates or prefer to avoid aortic valve replacement. (J Interven Cardiol 2011;24:92-98).
Gustav R Eles; Don L Fisher; Ramzi Khalil; Zuhdi Dajani; Jennifer P Spotti; David Lasorda
Related Documents :
9605079 - Ten years of experience with the modified ross procedure.
6530969 - Closed cardiovascular surgery in the first year of life--experience with 40 consecutive...
19026799 - Type a aortic dissection: has surgical outcome improved with time?
6190259 - Subvalvular aortic stenosis: long-term surgical results.
20837899 - Long-term clinical and hemodynamic performance of the hancock ii versus the perimount a...
12503039 - Experience with cerebral perfusion in total aortic arch replacement.
18159379 - Polyclonal intravenous immunoglobulin for the prophylaxis and treatment of infection in...
15324349 - Periodontal therapy: a novel non-drug-induced experimental model to study human inflamm...
17632299 - Current treatment of age-related macular degeneration.
Publication Detail:
Type:  Journal Article     Date:  2010-08-25
Journal Detail:
Title:  Journal of interventional cardiology     Volume:  24     ISSN:  1540-8183     ISO Abbreviation:  J Interv Cardiol     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-02-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8907826     Medline TA:  J Interv Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  92-8     Citation Subset:  IM    
Copyright Information:
©2010, Wiley Periodicals, Inc.
Allegheny General Hospital, Pittsburgh, Pennsylvania.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Natural hybridization between Rhododendron delavayi and R. cyanocarpum (Ericaceae), from morphologic...
Next Document:  Circadian alteration in neurobiology during protracted opiate withdrawal in rats.