Document Detail


Balint's syndrome in Alzheimer's disease: visuospatial functions.
MedLine Citation:
PMID:  2265983     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A subgroup of patients with Alzheimer's disease (AD) developed Balint's syndrome, an uncommon and incompletely understood disorder of visuospatial processing. We characterized the visuospatial features of three AD patients with Balint's syndrome and compared them to three comparably demented AD patients without this syndrome. On visuospatial tasks, the Balint patients were unable to integrate visual stimuli over space. On contrast sensitivity testing, the Balint patients had significantly decreased contrast sensitivities for low spatial frequency gratings (0.5, 1.0 and 2.0 cpd) alternated at 7.5 Hz. Furthermore, the Balint patients had left visual field attentional deficits and normal hemifield P100 visual evoked potentials. In AD, Balint's syndrome involved decreased sensitivity to low spatial frequencies necessary for global visuospatial analysis, a disturbance suggesting damage to the magnocellular visual system in the occipitoparietal association cortex and, possibly, in the optic nerves.
Authors:
M F Mendez; J Turner; G C Gilmore; B Remler; R L Tomsak
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The International journal of neuroscience     Volume:  54     ISSN:  0020-7454     ISO Abbreviation:  Int. J. Neurosci.     Publication Date:  1990 Oct 
Date Detail:
Created Date:  1991-02-12     Completed Date:  1991-02-12     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0270707     Medline TA:  Int J Neurosci     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  339-46     Citation Subset:  IM    
Affiliation:
Department of Neurology, St. Paul-Ramsey Medical Center/University of Minnesota 55101.
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MeSH Terms
Descriptor/Qualifier:
Aged
Alzheimer Disease / complications*
Contrast Sensitivity
Evoked Potentials, Visual
Female
Humans
Male
Middle Aged
Space Perception*
Syndrome
Vision Disorders / complications*,  diagnosis
Vision Tests
Visual Fields
Visual Perception*
Grant Support
ID/Acronym/Agency:
2P01AG04391/AG/NIA NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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