Document Detail

Baldness and coronary artery disease: the dermatologic point of view of a controversial issue.
MedLine Citation:
PMID:  11453815     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Several articles, most of them written by nondermatologists, have stressed that bald men have a higher risk for coronary artery disease than men who are not bald. This study was performed to evaluate the validity of such conclusions from a dermatologic point of view. DESIGN: A review of the 24 articles in literature from 1954 to 1999 as provided by MEDLINE and a previous review. RESULTS: Five articles contained simple comments; 1 was a review of the previous literature; and 3 dealt only with the lipid profile. The remaining 15 articles dealt with coronary artery disease and baldness, and 9 of these concluded that there is a relationship between the 2 conditions, especially in younger subjects with severe early-onset androgenetic alopecia. CONCLUSIONS: Baldness did not coincide with androgenetic alopecia in some of the articles examined, which makes it difficult to settle the issue. Subjects who develop baldness before their 30s may have a higher risk for coronary artery disease than other men, and they may be individuals with early-onset androgenetic alopecia who also present with particularly elevated dihydrotestosterone-testosterone ratios. The baldness theory should be included as a secondary hypothesis in large epidemiological studies of coronary artery disease. Such studies should include dermatologic expertise for accurate, cost-effective evaluation of baldness.
A Rebora
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Publication Detail:
Type:  Journal Article; Meta-Analysis; Review    
Journal Detail:
Title:  Archives of dermatology     Volume:  137     ISSN:  0003-987X     ISO Abbreviation:  Arch Dermatol     Publication Date:  2001 Jul 
Date Detail:
Created Date:  2001-07-16     Completed Date:  2001-07-26     Revised Date:  2008-03-17    
Medline Journal Info:
Nlm Unique ID:  0372433     Medline TA:  Arch Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  943-7     Citation Subset:  AIM; IM    
Department of Dermatology, Clinica Dermatologica, Viale Benedetto XV, 7, 16132 Genova, Italy.
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MeSH Terms
Age of Onset
Alopecia / classification,  epidemiology*
Bias (Epidemiology)
Case-Control Studies
Cohort Studies
Confidence Intervals
Coronary Disease / epidemiology*,  mortality*
Middle Aged
Odds Ratio
Prospective Studies
Reproducibility of Results
Research Design
Risk Assessment
Sample Size

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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