| Balancing the benefits of n-3 polyunsaturated fatty acids and the risks of methylmercury exposure from fish consumption. | |
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MedLine Citation:
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PMID: 21884130 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Fish and shellfish are widely available foods that provide important nutrients, particularly n-3 polyunsaturated fatty acids (n-3 PUFAs), to many populations globally. These nutrients, especially docosahexaenoic acid, confer benefits to brain and visual system development in infants and reduce risks of certain forms of heart disease in adults. However, fish and shellfish can also be a major source of methylmercury (MeHg), a known neurotoxicant that is particularly harmful to fetal brain development. This review documents the latest knowledge on the risks and benefits of seafood consumption for perinatal development of infants. It is possible to choose fish species that are both high in n-3 PUFAs and low in MeHg. A framework for providing dietary advice for women of childbearing age on how to maximize the dietary intake of n-3 PUFAs while minimizing MeHg exposures is suggested. |
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Authors:
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Kathryn R Mahaffey; Elsie M Sunderland; Hing Man Chan; Anna L Choi; Philippe Grandjean; Koenraad Mariën; Emily Oken; Mineshi Sakamoto; Rita Schoeny; Pál Weihe; Chong-Huai Yan; Akira Yasutake |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Nutrition reviews Volume: 69 ISSN: 1753-4887 ISO Abbreviation: Nutr. Rev. Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-09-02 Completed Date: 2012-01-05 Revised Date: 2012-09-28 |
Medline Journal Info:
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Nlm Unique ID: 0376405 Medline TA: Nutr Rev Country: United States |
Other Details:
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Languages: eng Pagination: 493-508 Citation Subset: IM |
Copyright Information:
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© 2011 International Life Sciences Institute. |
Affiliation:
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Department of Occupational and Environmental Health, George Washington University School of Public Health, Washington DC, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Child Child Development / drug effects Diet / adverse effects* Fatty Acids, Omega-3 / administration & dosage*, metabolism Female Food Contamination* / prevention & control Health Promotion Humans Infant Male Maternal Exposure / prevention & control Methylmercury Compounds / toxicity* Neurotoxicity Syndromes / etiology, prevention & control Risk Assessment Seafood / adverse effects*, analysis Water Pollutants, Chemical / toxicity* Young Adult |
| Grant Support | |
ID/Acronym/Agency:
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P30 DK040561-15/DK/NIDDK NIH HHS; P30 ES000002/ES/NIEHS NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Fatty Acids, Omega-3; 0/Methylmercury Compounds; 0/Water Pollutants, Chemical |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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