Document Detail


Balancing the benefits of n-3 polyunsaturated fatty acids and the risks of methylmercury exposure from fish consumption.
MedLine Citation:
PMID:  21884130     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Fish and shellfish are widely available foods that provide important nutrients, particularly n-3 polyunsaturated fatty acids (n-3 PUFAs), to many populations globally. These nutrients, especially docosahexaenoic acid, confer benefits to brain and visual system development in infants and reduce risks of certain forms of heart disease in adults. However, fish and shellfish can also be a major source of methylmercury (MeHg), a known neurotoxicant that is particularly harmful to fetal brain development. This review documents the latest knowledge on the risks and benefits of seafood consumption for perinatal development of infants. It is possible to choose fish species that are both high in n-3 PUFAs and low in MeHg. A framework for providing dietary advice for women of childbearing age on how to maximize the dietary intake of n-3 PUFAs while minimizing MeHg exposures is suggested.
Authors:
Kathryn R Mahaffey; Elsie M Sunderland; Hing Man Chan; Anna L Choi; Philippe Grandjean; Koenraad Mariën; Emily Oken; Mineshi Sakamoto; Rita Schoeny; Pál Weihe; Chong-Huai Yan; Akira Yasutake
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Nutrition reviews     Volume:  69     ISSN:  1753-4887     ISO Abbreviation:  Nutr. Rev.     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-09-02     Completed Date:  2012-01-05     Revised Date:  2013-06-27    
Medline Journal Info:
Nlm Unique ID:  0376405     Medline TA:  Nutr Rev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  493-508     Citation Subset:  IM    
Copyright Information:
© 2011 International Life Sciences Institute.
Affiliation:
Department of Occupational and Environmental Health, George Washington University School of Public Health, Washington DC, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Child
Child Development / drug effects
Diet / adverse effects*
Fatty Acids, Omega-3 / administration & dosage*,  metabolism
Female
Food Contamination* / prevention & control
Health Promotion
Humans
Infant
Male
Maternal Exposure / prevention & control
Methylmercury Compounds / toxicity*
Neurotoxicity Syndromes / etiology,  prevention & control
Risk Assessment
Seafood / adverse effects*,  analysis
Water Pollutants, Chemical / toxicity*
Young Adult
Grant Support
ID/Acronym/Agency:
P30 DK040561-15/DK/NIDDK NIH HHS; P30 ES000002/ES/NIEHS NIH HHS
Chemical
Reg. No./Substance:
0/Fatty Acids, Omega-3; 0/Methylmercury Compounds; 0/Water Pollutants, Chemical
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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