Document Detail


Bacteriophage bionanowire as a carrier for both cancer-targeting peptides and photosensitizers and its use in selective cancer cell killing by photodynamic therapy.
MedLine Citation:
PMID:  23047655     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A photosensitizer, pyropheophorbid-a (PPa), is conjugated to SKBR-3 breast cancer cell-specific biological nanowire phage, to form a novel PPa-phage complex, which is further successfully used in selectively killing SKBR-3 breast cancer cells by the mechanism of photodynamic therapy (PDT).
Authors:
Naveen Gandra; Gopal Abbineni; Xuewei Qu; Yanyan Huai; Li Wang; Chuanbin Mao
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2012-10-09
Journal Detail:
Title:  Small (Weinheim an der Bergstrasse, Germany)     Volume:  9     ISSN:  1613-6829     ISO Abbreviation:  Small     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-01-21     Completed Date:  2013-06-26     Revised Date:  2013-07-11    
Medline Journal Info:
Nlm Unique ID:  101235338     Medline TA:  Small     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  215-21     Citation Subset:  IM    
Copyright Information:
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Affiliation:
Department of Chemistry and Biochemistry, Stephenson Life Sciences Research Center, University of Oklahoma, Norman, OK 73019, USA.
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MeSH Terms
Descriptor/Qualifier:
Bacteriophages*
Cell Line, Tumor
Humans
Nanowires*
Peptides / administration & dosage*
Photochemotherapy*
Photosensitizing Agents / administration & dosage*
Grant Support
ID/Acronym/Agency:
1R21EB015190-01A1/EB/NIBIB NIH HHS; 4R03AR056848-03/AR/NIAMS NIH HHS; 5R01HL092526-02/HL/NHLBI NIH HHS; 5R21EB009909-02/EB/NIBIB NIH HHS; R01 HL092526/HL/NHLBI NIH HHS; R03 AR056848/AR/NIAMS NIH HHS; R21 EB009909/EB/NIBIB NIH HHS; R21 EB015190/EB/NIBIB NIH HHS
Chemical
Reg. No./Substance:
0/Peptides; 0/Photosensitizing Agents
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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