| Bacteriocins: safe, natural antimicrobials for food preservation. | |
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MedLine Citation:
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PMID: 11764886 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Bacteriocins are antibacterial proteins produced by bacteria that kill or inhibit the growth of other bacteria. Many lactic acid bacteria (LAB) produce a high diversity of different bacteriocins. Though these bacteriocins are produced by LAB found in numerous fermented and non-fermented foods, nisin is currently the only bacteriocin widely used as a food preservative. Many bacteriocins have been characterized biochemically and genetically, and though there is a basic understanding of their structure-function, biosynthesis, and mode of action, many aspects of these compounds are still unknown. This article gives an overview of bacteriocin applications, and differentiates bacteriocins from antibiotics. A comparison of the synthesis. mode of action, resistance and safety of the two types of molecules is covered. Toxicity data exist for only a few bacteriocins, but research and their long-time intentional use strongly suggest that bacteriocins can be safely used. |
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Authors:
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J Cleveland; T J Montville; I F Nes; M L Chikindas |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review |
Journal Detail:
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Title: International journal of food microbiology Volume: 71 ISSN: 0168-1605 ISO Abbreviation: Int. J. Food Microbiol. Publication Date: 2001 Dec |
Date Detail:
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Created Date: 2001-12-17 Completed Date: 2001-12-28 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8412849 Medline TA: Int J Food Microbiol Country: Netherlands |
Other Details:
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Languages: eng Pagination: 1-20 Citation Subset: IM |
Affiliation:
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Department of Food Science, Rutgers, The State University of New Jersey, New Brunswick 08901, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anti-Bacterial Agents
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biosynthesis,
chemistry,
classification,
pharmacology* Bacteriocins / biosynthesis, chemistry, classification, pharmacology* Drug Resistance, Microbial Food Preservation / methods* Lactobacillus / metabolism* Nisin / biosynthesis, chemistry, classification, pharmacology Safety Structure-Activity Relationship |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 0/Bacteriocins; 1414-45-5/Nisin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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