Document Detail


Bacterial vaginosis in early pregnancy is associated with low birth weight and small for gestational age, but not with spontaneous preterm birth: a population-based study on Danish women.
MedLine Citation:
PMID:  16492583     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To analyze the association between bacterial vaginosis (BV) in early pregnancy and preterm birth, low birth weight (LBW) and small for gestational age (SGA) in a Danish population. METHODS: A geographically defined population-based prospective study of Danish-speaking pregnant women over18 years of age enrolled before week 24 and followed until delivery. BV was diagnosed by Amsel's clinical criteria at enrolment. RESULTS: At enrolment, 13.7% had BV. BV was not associated with an increased risk of spontaneous preterm birth (crude OR 0.8 (0.5-1.5)). Nulliparity was found to affect birth weight to such a degree that this variable was used for stratification. In nulliparous women BV was associated with LBW (adj. OR 4.3 (1.5-12)) and SGA (adj. OR 1.6 (0.7-3.1)) compared to nulliparous without BV. No such associations were seen for multiparous women with BV. CONCLUSIONS: BV was not associated with spontaneous preterm birth, but was associated with both LBW and SGA in nulliparous women.
Authors:
Poul Thorsen; Ida Vogel; Jørn Olsen; Bernard Jeune; Jes G Westergaard; Bo Jacobsson; Birger R Møller
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  19     ISSN:  1476-7058     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2006 Jan 
Date Detail:
Created Date:  2006-02-22     Completed Date:  2006-08-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1-7     Citation Subset:  IM    
Affiliation:
Department of Obsterics and Gynecology, Odense University Hospital, Denmark.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Denmark / epidemiology
Female
Humans
Hydrogen-Ion Concentration
Infant, Low Birth Weight*
Infant, Newborn
Infant, Small for Gestational Age*
Parity
Predictive Value of Tests
Pregnancy
Pregnancy Complications, Infectious / diagnosis,  epidemiology*
Pregnancy Trimester, Second
Premature Birth*
Prospective Studies
Sensitivity and Specificity
Vagina / chemistry
Vaginosis, Bacterial / diagnosis,  epidemiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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