Document Detail


Bacterial meningitis in children.
MedLine Citation:
PMID:  12826449     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This review comprises aspects of the epidemiology, microbiology, pathophysiology, clinical manifestations, diagnosis, management, prognosis, and prevention of bacterial meningitis, with emphasis on the paediatric population. The beginning of this millennium has witnessed the virtual disappearance of Haemophilus invasive disease in some countries, emergence of pneumococcal strains that are resistant to multiple antibiotics, isolation of pneumococci with tolerance to vancomycin, outbreaks and clusters of meningococcal meningitis in several geographical areas, and intense research in development of effective conjugate pneumococcal and meningococcal vaccines. Bacterial meningitis has become an uncommon disease in the developed world. Unfortunately, because of limited economic resources and poor living conditions, many developing countries are still affected by the devastating consequences of this life-threatening systemic infection. Basic and clinical research is needed to discover new antimicrobial and anti-inflammatory agents to improve outcome from disease. Novel strategies are needed to distribute and implement effective vaccines worldwide to prevent bacterial meningitis.
Authors:
Xavier Sáez-Llorens; George H McCracken
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Lancet     Volume:  361     ISSN:  1474-547X     ISO Abbreviation:  Lancet     Publication Date:  2003 Jun 
Date Detail:
Created Date:  2003-06-26     Completed Date:  2003-07-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2985213R     Medline TA:  Lancet     Country:  England    
Other Details:
Languages:  eng     Pagination:  2139-48     Citation Subset:  AIM; IM    
Affiliation:
University of Panama School of Medicine, Hospital del Niño, Panama City, Panama. xsaezll@cwpanama.net
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MeSH Terms
Descriptor/Qualifier:
Child
Humans
Meningitis, Bacterial* / diagnosis,  epidemiology,  etiology,  physiopathology,  therapy
Prognosis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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