Document Detail


Bacterial meningitis in Hong Kong: 10-years' experience.
MedLine Citation:
PMID:  16023529     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: We studied the etiology, clinical features and outcome of patients with bacterial meningitis from an urban Chinese city over a 10-years period. METHODS: We reviewed the files of all persons aged 15-years old or above diagnosed with community-acquired bacterial meningitis from a regional hospital. The clinical findings, relevant laboratory and imaging results as well as outcome were recorded in cases with microbiological evidence of meningitis. Neurosurgical and pediatric patients were excluded. RESULTS: Sixty-five patients between the ages of 15 and 86 years of age (mean 52 years) were identified of whom 18 (28%) died. The four most common causes were Mycobacteria tuberculosis (46%), Streptococcus pneumoniae (11%), Streptococcus suis (9%) and Klebsiella pneumoniae (8%). Neisseria meningitidis and Haemophilus influenzae were rare pathogens. The annual incidence of community-acquired bacterial meningitis was 1.27/100,000 adults. Delay in treatment was associated with a poorer prognosis (p<0.001, OR=38.84, CI=7.33-205.80). CONCLUSION: The causative organisms found in this region of China differ from that reported from Europe and the US; tuberculous meningitis is the most common cause of bacterial meningitis.
Authors:
A C F Hui; K C Ng; P Y Tong; V Mok; K M Chow; A Wu; L K S Wong
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Publication Detail:
Type:  Journal Article     Date:  2004-11-11
Journal Detail:
Title:  Clinical neurology and neurosurgery     Volume:  107     ISSN:  0303-8467     ISO Abbreviation:  Clin Neurol Neurosurg     Publication Date:  2005 Aug 
Date Detail:
Created Date:  2005-07-18     Completed Date:  2005-10-11     Revised Date:  2009-10-14    
Medline Journal Info:
Nlm Unique ID:  7502039     Medline TA:  Clin Neurol Neurosurg     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  366-70     Citation Subset:  IM    
Affiliation:
Department of Medicine, Prince of Wales Hospital, The Chinese University of Hong Kong, Ngan Shing Street, New Terriotories, Shatin, Hong Kong SAR. cfhui@cuhk.edu.hk
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Age Factors
Aged
Aged, 80 and over
Community-Acquired Infections / cerebrospinal fluid,  epidemiology,  etiology
Female
Hong Kong / epidemiology
Humans
Incidence
Male
Meningitis, Bacterial / cerebrospinal fluid,  epidemiology*,  etiology
Middle Aged
Prognosis
Sex Factors
Survival Rate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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