Document Detail

Bacterial endocarditis due to Haemophilus parainfluenzae.
MedLine Citation:
PMID:  832483     Owner:  NLM     Status:  MEDLINE    
We have evaluated three patients with Haemophilus parainfluenzae endocarditis. Two of the three had underlying heart disease. All presented with fever, chills and malaise of less than two weeks' duration. Mitral valve involvement led to congestive heart failure in two of three cases. Treatment proved difficult, despite normally adequate dosages of antibiotics to which the pathogens were sensitive in vitro (ampicillin, 12-20 gm/dag; gentamicin, 3-5 mg/kg/day). Two patients were cured; one died. There was a suggestion of an inverse correlation between vegetation mass and favorable clinical response. Review of the English literature disclosed 22 documented cases of H parainfluenzae endocarditis, including 12 in the antibiotic era.
D C Blair; W Walker; T Sodeman; T Pagano
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Chest     Volume:  71     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  1977 Feb 
Date Detail:
Created Date:  1977-03-31     Completed Date:  1977-03-31     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  146-9     Citation Subset:  AIM; IM    
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MeSH Terms
Ampicillin / therapeutic use
Endocarditis, Bacterial / drug therapy,  etiology*,  pathology
Gentamicins / therapeutic use
Haemophilus Infections* / drug therapy,  pathology
Microbial Sensitivity Tests
Middle Aged
Reg. No./Substance:
0/Gentamicins; 69-53-4/Ampicillin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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