Document Detail

Bacterial cytokinesis: From Z ring to divisome.
MedLine Citation:
PMID:  22888013     Owner:  NLM     Status:  MEDLINE    
Ancestral homologues of the major eukaryotic cytoskeletal families, tubulin and actin, play critical roles in cytokinesis of bacterial cells. FtsZ is the ancestral homologue of tubulin and assembles into the Z ring that determines the division plane. FtsA, a member of the actin family, is involved in coordinating cell wall synthesis during cytokinesis. FtsA assists in the formation of the Z ring and also has a critical role in recruiting downstream division proteins to the Z ring to generate the divisome that divides the cell. Spatial regulation of cytokinesis occurs at the stage of Z ring assembly and regulation of cell size occurs at this stage or during Z ring maturation.
Joe Lutkenhaus; Sebastien Pichoff; Shishen Du
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review     Date:  2012-08-30
Journal Detail:
Title:  Cytoskeleton (Hoboken, N.J.)     Volume:  69     ISSN:  1949-3592     ISO Abbreviation:  Cytoskeleton (Hoboken)     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-23     Completed Date:  2013-03-21     Revised Date:  2014-07-24    
Medline Journal Info:
Nlm Unique ID:  101523844     Medline TA:  Cytoskeleton (Hoboken)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  778-90     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Wiley Periodicals, Inc.
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MeSH Terms
Bacteria / cytology*,  growth & development,  metabolism
Bacterial Proteins / chemistry,  metabolism
Models, Biological
Spores, Bacterial / physiology
Grant Support
Reg. No./Substance:
0/Bacterial Proteins

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