Document Detail


Bacterial cytokinesis: From Z ring to divisome.
MedLine Citation:
PMID:  22888013     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Ancestral homologues of the major eukaryotic cytoskeletal families, tubulin and actin, play critical roles in cytokinesis of bacterial cells. FtsZ is the ancestral homologue of tubulin and assembles into the Z ring that determines the division plane. FtsA, a member of the actin family, is involved in coordinating cell wall synthesis during cytokinesis. FtsA assists in the formation of the Z ring and also has a critical role in recruiting downstream division proteins to the Z ring to generate the divisome that divides the cell. Spatial regulation of cytokinesis occurs at the stage of Z ring assembly and regulation of cell size occurs at this stage or during Z ring maturation.
Authors:
Joe Lutkenhaus; Sebastien Pichoff; Shishen Du
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review     Date:  2012-08-30
Journal Detail:
Title:  Cytoskeleton (Hoboken, N.J.)     Volume:  69     ISSN:  1949-3592     ISO Abbreviation:  Cytoskeleton (Hoboken)     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-23     Completed Date:  2013-03-21     Revised Date:  2014-07-24    
Medline Journal Info:
Nlm Unique ID:  101523844     Medline TA:  Cytoskeleton (Hoboken)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  778-90     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Wiley Periodicals, Inc.
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MeSH Terms
Descriptor/Qualifier:
Bacteria / cytology*,  growth & development,  metabolism
Bacterial Proteins / chemistry,  metabolism
Cytokinesis*
Models, Biological
Spores, Bacterial / physiology
Grant Support
ID/Acronym/Agency:
GM29764/GM/NIGMS NIH HHS; R01 GM029764/GM/NIGMS NIH HHS
Chemical
Reg. No./Substance:
0/Bacterial Proteins
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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