| Bacterial cytokinesis: from Z ring to divisome. | |
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MedLine Citation:
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PMID: 22888013 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Ancestral homologues of the major eukaryotic cytoskeletal families, tubulin and actin, play critical roles in cytokinesis of bacterial cells. FtsZ is the ancestral homologue of tubulin and assembles into the Z ring that determines the division plane. FtsA, a member of the actin family, is involved in coordinating cell wall synthesis during cytokinesis. FtsA assists in the formation of the Z ring and also has a critical role in recruiting downstream division proteins to the Z ring to generate the divisome that divides the cell. Spatial regulation of cytokinesis occurs at the stage of Z ring assembly and regulation of cell size occurs at this stage or during Z ring maturation. © 2012 Wiley-Blackwell, Inc. |
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Authors:
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Joe Lutkenhaus; Sebastien Pichoff; Shishen Du |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-8-6 |
Journal Detail:
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Title: Cytoskeleton (Hoboken, N.J.) Volume: - ISSN: 1949-3592 ISO Abbreviation: Cytoskeleton (Hoboken) Publication Date: 2012 Aug |
Date Detail:
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Created Date: 2012-8-13 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101523844 Medline TA: Cytoskeleton (Hoboken) Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 Wiley Periodicals, Inc. |
Affiliation:
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Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, KS 66160. jlutkenh@kumc.edu. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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