| Bacterial chromosome segregation. | |
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MedLine Citation:
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PMID: 12142478 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Recent studies have made great strides toward our understanding of the mechanisms of microbial chromosome segregation and partitioning. This review first describes the mechanisms that function to segregate newly replicated chromosomes, generating daughter molecules that are viable substrates for partitioning. Then experiments that address the mechanisms of bulk chromosome movement are summarized. Recent evidence indicates that a stationary DNA replication factory may be responsible for supplying the force necessary to move newly duplicated DNA toward the cell poles. Some factors contributing to the directionality of chromosome movement probably include centromere-like-binding proteins, DNA condensation proteins, and DNA translocation proteins. |
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Authors:
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Geoffrey C Draper; James W Gober |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.; Review Date: 2002-01-30 |
Journal Detail:
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Title: Annual review of microbiology Volume: 56 ISSN: 0066-4227 ISO Abbreviation: Annu. Rev. Microbiol. Publication Date: 2002 |
Date Detail:
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Created Date: 2002-09-05 Completed Date: 2003-01-21 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0372370 Medline TA: Annu Rev Microbiol Country: United States |
Other Details:
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Languages: eng Pagination: 567-97 Citation Subset: IM |
Affiliation:
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Department of Chemistry and Biochemistry, University of California, Los Angeles, 90095-1569, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Bacterial Proteins
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genetics,
metabolism Bacteriophages / genetics, metabolism Cell Separation / methods Chromosome Segregation / physiology* Chromosomes, Bacterial / genetics*, metabolism DNA Replication DNA Topoisomerases, Type I, Bacterial / genetics, metabolism Escherichia coli / genetics, growth & development Models, Genetic Mutation Plasmids / metabolism Spores, Bacterial / genetics, metabolism |
| Grant Support | |
ID/Acronym/Agency:
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GM48417/GM/NIGMS NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Bacterial Proteins; 0/chromosome partition proteins, bacterial; EC 5.99.1.-/DNA Topoisomerases, Type I, Bacterial |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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